Pituitary macroadenoma: analysis of intercarotid artery distance compared to controls



Document title: Pituitary macroadenoma: analysis of intercarotid artery distance compared to controls
Journal: Arquivos de neuro-psiquiatria
Database: PERIÓDICA
System number: 000393637
ISSN: 0004-282X
Authors: 1
1
1
1
2
Institutions: 1Hospital da Forca Aerea do Galeao, Departamento de Neurocirugia, Rio de Janeiro. Brasil
2Universidade Federal Fluminense, Departamento de Neurocirurgia, Niteroi, Rio de Janeiro. Brasil
Year:
Season: May
Volumen: 74
Number: 5
Pages: 396-404
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract To evaluate the intercarotid distance (ICD) of patients with pituitary macroadenoma and compare to heatlhy controls. Method We retrospectively reviewed contrast-enhanced MRI images from twenty consecutive patients diagnosed with non-functioning pituitary macroadenoma, measured the ICD at two different levels (petrous segment – ICD1 and horizontal cavernous segment – ICD2) and compared to twenty paired controls. Results There was no statistically significant difference of the mean ICD1 between the groups and subgroups. For the ICD2 there was statistically significant difference between the case and controls. However, there was no significant difference between the patients with smaller adenomas and the controls. In contrast, the patients with giant adenomas showed statistically significantly higher ICD2 than the controls. Conclusion The ICD at the horizontal segment of the cavernous carotid tends to be wider in patients with giant pituitary adenomas than in healthy individuals or patients with smaller adenomas
Portuguese abstract Avaliar a distância intercarotídea (DIC) de pacientes com macroadenoma de hipófise e comparar com controles saudáveis. Método Foram analisados retrospectivamente imagens de ressonância magnética com contraste de vinte pacientes consecutivos com diagnóstico de macroadenoma hipofisário não-funcionante, medidas as DIC em dois níveis diferentes (segmento petroso – DIC1 e segmento cavernoso horizontal – DIC2) e comparados com vinte controles pareados. Resultados Não houve diferença estatisticamente significativa da DIC1 média entre os grupos e subgrupos. Para a DIC2 houve diferença estatisticamente significativa entre os casos e controles. No entanto, não houve diferença significativa entre os doentes com adenomas menores e os controles. Entretanto, os pacientes com adenomas gigantes tiveram estatisticamente significativamente DIC2 que os controlos. Conclusão A DIC no segmento horizontal da carótida cavernoso, tende a ser mais larga em doentes com adenomas hipofisários gigantes do que em indivíduos saudáveis ou de pacientes com adenomas menores
Disciplines: Medicina
Keyword: Endocrinología,
Neurología,
Macroadenoma,
Hipófisis,
Carótida interna,
Endoscopia
Keyword: Medicine,
Endocrinology,
Neurology,
Pituitary macroadenoma,
Internal carotid artery,
Endoscopy
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