Changes in thyroid function status of suicidal patients



Document title: Changes in thyroid function status of suicidal patients
Journal: Archives of clinical psychiatry
Database: PERIÓDICA
System number: 000419338
Authors: 1
1
1
2
3
1
3
Institutions: 1Government College University, Department of Chemistry, Lahore, Punjab. Pakistán
2Mayo Hospital, Lahore, Centre for Nuclear Medicine, Lahore, Punjab. Pakistán
3COMSATS Institute of Information Technology, Department of Chemistry, Abbottabad. Pakistán
Year:
Season: Ene-Feb
Volumen: 45
Number: 1
Pages: 12-14
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract This study was carried out at Punjab Institute of Mental Health and Centre for Nuclear Medicine Mayo Hospital, Lahore. It is aimed at the possible association of thyroid malfunctioning with suicide attempts of patients. Objective: Determination of thyroid function status of suicidal psychiatric patients and their comparison with psychiatric patients without suicide attempt or ideation. Methods: Total 54 patients with either past history of suicide attempt or current suicidal ideation were selected for analysis of their thyroid function status (age 15-55 years). Age matched 50 non-suicide psychiatric patients were included for comparison. Results: Two patients with suicide attempt had overt thyroid dysfunction. Remaining patients had serum FT4, FT3 and TSH level within normal range. Suicide attempter patients had lower FT4 but increased FT3 and TSH levels compared to suicidal ideation patients. Serum FT4 and TSH levels in suicidal patients were not different from psychiatric patients. Serum FT3 in suicidal patients was lower than psychiatric patients (3.7 ± 0.8 vs. 4.3 ± 0.5; p < 0.05). Female suicidal patients had lower FT3 levels compared to male patients (3.4 ± 0.6 vs. 3.9 ± 0.8 pmol/L; p < 0.05). Discussion: Local suicidal patients have higher incidence of overt thyroid disorder and lower FT3 levels compared to non-suicidal psychiatric patients
Disciplines: Medicina
Keyword: Psiquiatría,
Endocrinología,
Función tiroidea,
Hormona tiroidea,
Depresión,
Pacientes psiquiátricos,
Suicidio
Keyword: Psychiatry,
Endocrinology,
Thyroid function,
Thyroid hormones,
Depression,
Psychiatric patients,
Suicide
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