| Journal: | ARBS. Annual review of biomedical sciences |
| Database: | PERIÓDICA |
| System number: | 000396639 |
| ISSN: | 1517-3011 |
| Authors: | Kurek, Nicholas S1 Chandra, Sathees B1 |
| Institutions: | 1Roosevelt University, Department of Biological, Chemical and Physical Sciences, Chicago, Illinois. Estados Unidos de América |
| Year: | 2012 |
| Volumen: | 14 |
| Pages: | 1-15 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Nanotechnology involves probing and manipulating matter at the molecular level. Nanotechnology based molecular diagnostics have the potential to alleviate the suffering caused by many diseases, including neurological disorders, due to the unique properties of nanomaterials. Most neurological illnesses are multifactorial conditions and many of these are also classified as neurobehavioral disorders. Alzheimer’s disease, Parkinson’s disease, Huntington disease, cerebral ischemia, epilepsy, schizophrenia and autism spectrum disorders like Rett syndrome are some examples of neurological disorders that could be better treated, diagnosed, prevented and possibly cured using nanotechnology. In order to improve the quality of life for disease afflicted people, a wide range of nanomaterials that include gold and silica nanoparticles, quantum dots and DNA along with countless other forms of nanotechnology have been investigated regarding their usefulness in advancing molecular diagnostics. Other small scaled materials like viruses and proteins also have potential for use as molecular diagnostic tools. Information obtained from nanotechnology based diagnostics can be stored and manipulated using bioinformatics software. More advanced nanotechnology based diagnostic procedures for the acquisition of even greater proteomic and genomic knowledge can then be developed along with better ways to fight various diseases. Nanotechnology also has numerous applications besides those related to biotechnology and medicine. In this article, we will discuss and analyze many novel nanotechnology based diagnostic techniques at our disposal today |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Neurología, Trastornos neurológicos, Diagnóstico molecular, Nanopartículas, Bioinformática, Enfermedades multifactoriales |
| Keyword: | Medicine, Diagnosis, Neurology, Neurological disorders, Molecular diagnosis, Nanoparticles, Bioinformatics, Multifactorial diseases |
| Full text: | Texto completo (Ver PDF) |
