Subacute liver failure by pseudocirrhotic metastatic breast cancer infiltration



Document title: Subacute liver failure by pseudocirrhotic metastatic breast cancer infiltration
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000415675
ISSN: 1665-2681
Authors: 1
2
3
1
1
Institutions: 1Saarland University Medical Center, Department of Medicine II, Homburg. Alemania
2Saarland University Medical Center, Institute of Pathology, Homburg. Alemania
3Saarland University Medical Center, Institute of Diagnostic and Interventional Radiology, Homburg. Alemania
Year:
Season: Sep-Oct
Volumen: 12
Number: 5
Pages: 834-836
Country: México
Language: Inglés
Document type: Artículo
Approach: Caso clínico
English abstract Hepatic metastases are common in the clinical course of breast cancer and typically appear as mass lesions. This report describes the case of a 70-year-old woman with a history of breast cancer and no previously known liver disease presenting with the first episode of variceal bleeding and subacute hepatic failure. Imaging studies indicated liver cirrhosis without signs of malignant focal lesions. Comprehensive diagnostic work-up was negative for specific causes of liver disease and provided no evidence for tumor recurrence. Finally transjugular liver biopsy revealed a marked diffuse desmoplastic infiltration by breast cancer cells. Malignant pseudocirrhosis is an unusual pattern of metastatic tumor, spread representing a rare but important differential diagnosis of progressive liver failure. Liver biopsy is the key procedure to establish the diagnosis as imaging studies may mimic cirrhosis
Disciplines: Medicina
Keyword: Gastroenterología,
Oncología,
Cirrosis hepática,
Trasplante de hígado,
Metástasis,
Falla hepática
Keyword: Medicine,
Gastroenterology,
Oncology,
Liver cirrhosis,
Liver transplantation,
Metastasis,
Liver failure
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