Subacute liver failure by pseudocirrhotic metastatic breast cancer infiltration



Título del documento: Subacute liver failure by pseudocirrhotic metastatic breast cancer infiltration
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000415675
ISSN: 1665-2681
Autores: 1
2
3
1
1
Instituciones: 1Saarland University Medical Center, Department of Medicine II, Homburg. Alemania
2Saarland University Medical Center, Institute of Pathology, Homburg. Alemania
3Saarland University Medical Center, Institute of Diagnostic and Interventional Radiology, Homburg. Alemania
Año:
Periodo: Sep-Oct
Volumen: 12
Número: 5
Paginación: 834-836
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Hepatic metastases are common in the clinical course of breast cancer and typically appear as mass lesions. This report describes the case of a 70-year-old woman with a history of breast cancer and no previously known liver disease presenting with the first episode of variceal bleeding and subacute hepatic failure. Imaging studies indicated liver cirrhosis without signs of malignant focal lesions. Comprehensive diagnostic work-up was negative for specific causes of liver disease and provided no evidence for tumor recurrence. Finally transjugular liver biopsy revealed a marked diffuse desmoplastic infiltration by breast cancer cells. Malignant pseudocirrhosis is an unusual pattern of metastatic tumor, spread representing a rare but important differential diagnosis of progressive liver failure. Liver biopsy is the key procedure to establish the diagnosis as imaging studies may mimic cirrhosis
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Oncología,
Cirrosis hepática,
Trasplante de hígado,
Metástasis,
Falla hepática
Keyword: Medicine,
Gastroenterology,
Oncology,
Liver cirrhosis,
Liver transplantation,
Metastasis,
Liver failure
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