| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000411848 |
| ISSN: | 1665-2681 |
| Authors: | Soza, Alejandro1 Labbé, Pilar1 Arrese, Marco1 Riquelme, Arnoldo1 Barrera, Francisco1 Benítez, Carlos1 Huete, Alvaro1 Balcells, M. Elvira1 Labarca, Jaime1 |
| Institutions: | 1Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile |
| Year: | 2015 |
| Season: | Ene-Feb |
| Volumen: | 14 |
| Number: | 1 |
| Pages: | 132-136 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, descriptivo |
| English abstract | The first generation protease inhibitors has been the mainstay of hepatitis C treatment for the last couple of years, showing marked improvement in sustained virological response, but also increased side effects. Infection has emerged as a common complication of telaprevir and boceprevir in combination with peginterferon and ribavirin, usually caused by common pathogens. We present the case of a 65 years old man who developed a Mycobacterium abscessus pulmonary infection during treatment with telaprevir, peginterferon and ribavirin. The patient was successfully treated with amikacin, imipenem and chlarithromycin. The present case is relevant for increasing awareness for recognition of opportunistic infections and particularly nontuberculous mycobacterial infections in patients receiving triple therapy for chronic hepatitis C, especially in cirrhotic subjects who develop significant lymphopenia |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Terapéutica y rehabilitación, Hepatitis C, Boceprevir, Peginterferon, Ribavirina, Infecciones oportunistas, Mycobacterium abscessus, Linfopenia |
| Keyword: | Medicine, Gastroenterology, Therapeutics and rehabilitation, Hepatitis C, Boceprevir, Peginterferon, Ribavirin, Opportunistic infections, Mycobacterium abscessus, Lymphopenia |
| Full text: | Texto completo (Ver PDF) |
