Mycobacterium abscessus pulmonary infection during hepatitis C treatment with telaprevir, peginterferon and ribavirin



Título del documento: Mycobacterium abscessus pulmonary infection during hepatitis C treatment with telaprevir, peginterferon and ribavirin
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000411848
ISSN: 1665-2681
Autors: 1
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Institucions: 1Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile
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Període: Ene-Feb
Volum: 14
Número: 1
Paginació: 132-136
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, descriptivo
Resumen en inglés The first generation protease inhibitors has been the mainstay of hepatitis C treatment for the last couple of years, showing marked improvement in sustained virological response, but also increased side effects. Infection has emerged as a common complication of telaprevir and boceprevir in combination with peginterferon and ribavirin, usually caused by common pathogens. We present the case of a 65 years old man who developed a Mycobacterium abscessus pulmonary infection during treatment with telaprevir, peginterferon and ribavirin. The patient was successfully treated with amikacin, imipenem and chlarithromycin. The present case is relevant for increasing awareness for recognition of opportunistic infections and particularly nontuberculous mycobacterial infections in patients receiving triple therapy for chronic hepatitis C, especially in cirrhotic subjects who develop significant lymphopenia
Disciplines Medicina
Paraules clau: Gastroenterología,
Terapéutica y rehabilitación,
Hepatitis C,
Boceprevir,
Peginterferon,
Ribavirina,
Infecciones oportunistas,
Mycobacterium abscessus,
Linfopenia
Keyword: Medicine,
Gastroenterology,
Therapeutics and rehabilitation,
Hepatitis C,
Boceprevir,
Peginterferon,
Ribavirin,
Opportunistic infections,
Mycobacterium abscessus,
Lymphopenia
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