Liver transplantation followed by autologous stem cell transplantation for acute liver failure caused by AL amyloidosis. Case report and review of the literature
Document title: Liver transplantation followed by autologous stem cell transplantation for acute liver failure caused by AL amyloidosis. Case report and review of the literature
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000407488
ISSN: 1665-2681
Authors: 1
2
3
2
2
2
Institutions: 1Cairo University, El Cairo. Egipto
2Technische Universitat Munchen, Munich, Baviera. Alemania
Year:
Season: Jul-Ago
Volumen: 15
Number: 4
Pages: 592-597
Country: México
Language: Inglés
Document type: Artículo
Approach: Caso clínico
English abstract Hepatic involvement in AL amyloidosis may present as acute liver failure. Historically, liver transplantation in these cases has achieved poor outcomes due to progress of amyloidosis and non-hepatic organ damage. In the era of bortezomib treatment, the prognosis of AL amyloidosis has been markedly improved and may also result in better post-transplant outcomes. We present a case of isolated acute liver failure caused by AL amyloidosis, bridged to transplantation with bortezomib and treated with sequential orthotopic liver transplantation (OLT) and autologous stem cell transplantation. The patient is in stable remission 3 years after OLT
Disciplines: Medicina
Keyword: Cirugía,
Gastroenterología,
Amiloidosis,
Insuficiencia hepática aguda,
Trasplante de hígado
Keyword: Medicine,
Gastroenterology,
Surgery,
Amyloidosis,
Acute liver failure,
Liver transplantation
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