Liver transplantation followed by autologous stem cell transplantation for acute liver failure caused by AL amyloidosis. Case report and review of the literature
Título del documento: Liver transplantation followed by autologous stem cell transplantation for acute liver failure caused by AL amyloidosis. Case report and review of the literature
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000407488
ISSN: 1665-2681
Autors: 1
2
3
2
2
2
Institucions: 1Cairo University, El Cairo. Egipto
2Technische Universitat Munchen, Munich, Baviera. Alemania
Any:
Període: Jul-Ago
Volum: 15
Número: 4
Paginació: 592-597
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Hepatic involvement in AL amyloidosis may present as acute liver failure. Historically, liver transplantation in these cases has achieved poor outcomes due to progress of amyloidosis and non-hepatic organ damage. In the era of bortezomib treatment, the prognosis of AL amyloidosis has been markedly improved and may also result in better post-transplant outcomes. We present a case of isolated acute liver failure caused by AL amyloidosis, bridged to transplantation with bortezomib and treated with sequential orthotopic liver transplantation (OLT) and autologous stem cell transplantation. The patient is in stable remission 3 years after OLT
Disciplines Medicina
Paraules clau: Cirugía,
Gastroenterología,
Amiloidosis,
Insuficiencia hepática aguda,
Trasplante de hígado
Keyword: Medicine,
Gastroenterology,
Surgery,
Amyloidosis,
Acute liver failure,
Liver transplantation
Text complet: Texto completo (Ver PDF)