| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000436240 |
| ISSN: | 0001-3765 |
| Authors: | Veber, Bruno1 Camargo, Anderson1 Dalmagro, Ana Paula1 Bonde, Henrique Luis P1 Magro, Débora D. dal1 Lima, Daniela D. de2 Zeni, Ana Lúcia B1 |
| Institutions: | 1Universidade Regional de Blumenau, Departamento de Ciencias Naturais, Blumenau, Santa Catarina. Brasil 2Universidade da Regiao de Joinville, Departamento de Medicina, Joinville, Santa Catarina. Brasil |
| Year: | 2020 |
| Volumen: | 92 |
| Number: | 1 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Red cabbage (Brassica oleracea L. var. capitata f. rubra DC.) extract has been demonstrated hypolipidemic and antioxidant capacity. Herein, we investigated the effect of red cabbage aqueous extract (RC) or fenofibrate (FF) in oxidative stress induced by Triton WR-1339 in rats. The antioxidant capacity was evaluated through the superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities and, thiobarbituric reactive species (TBARS) and protein carbonyl (PC) levels in erythrocytes, liver, kidneys, cerebral cortex and hippocampus of male rats. The alterations promoted by Triton WR-1339 in enzymatic antioxidant defense in the liver, kidneys and hippocampus were reversed by RC or FF treatments. The TBARS and PC levels increased in the liver, cerebral cortex and hippocampus of hyperlipidemic rats were decreased by the treatments with RC or FF. These findings demonstrated that RC is a potential therapy to treat diseases not only involving dyslipidemic condition but also oxidative stress |
| Disciplines: | Medicina, Química |
| Keyword: | Medicina experimental, Hortalizas, Extractos vegetales, Actividad antioxidante, Estrés oxidativo, Col morada, Brassica oleracea, Brassicaceae |
| Keyword: | Experimental medicine, Vegetables, Plant extracts, Antioxidant activity, Red cabbage, Brassica oleracea, Oxidative stress, Brassicaceae |
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