An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy



Document title: An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000419770
ISSN: 0001-3765
Authors: 1
1
1
2
1
1
Institutions: 1Universidade de Aveiro, Departamento de Quimica, Aveiro. Portugal
2Universidade de Aveiro, Departamento de Ciencias Biomedicas, Aveiro. Portugal
Year:
Season: May
Volumen: 90
Number: 1
Pages: 1101-1130
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment
Disciplines: Medicina,
Química
Keyword: Química farmacéutica,
Oncología,
Terapia fotodinámica,
Liberación de fármacos,
Liposomas,
Nanopartículas de sílice,
Nanopartículas de oro,
Micelas poliméricas
Keyword: Medicinal chemistry,
Oncology,
Photodynamic therapy,
Drug delivery,
Liposomes,
Silica nanoparticles,
Gold nanoparticles,
Polymeric micelles
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