Journal: | Anais da Academia Brasileira de Ciencias |
Database: | PERIÓDICA |
System number: | 000419770 |
ISSN: | 0001-3765 |
Authors: | Mesquita, Mariana Q1 Dias, Cristina J1 Gamelas, Sara1 Fardilha, Margarida2 Neves, Maria G.P.M.S1 Faustino, Maria Amparo F1 |
Institutions: | 1Universidade de Aveiro, Departamento de Quimica, Aveiro. Portugal 2Universidade de Aveiro, Departamento de Ciencias Biomedicas, Aveiro. Portugal |
Year: | 2018 |
Season: | May |
Volumen: | 90 |
Number: | 1 |
Pages: | 1101-1130 |
Country: | Brasil |
Language: | Inglés |
Document type: | Artículo |
Approach: | Experimental, aplicado |
English abstract | Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment |
Disciplines: | Medicina, Química |
Keyword: | Química farmacéutica, Oncología, Terapia fotodinámica, Liberación de fármacos, Liposomas, Nanopartículas de sílice, Nanopartículas de oro, Micelas poliméricas |
Keyword: | Medicinal chemistry, Oncology, Photodynamic therapy, Drug delivery, Liposomes, Silica nanoparticles, Gold nanoparticles, Polymeric micelles |
Full text: | Texto completo (Ver HTML) |