An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy



Título del documento: An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy
Revista: Anais da Academia Brasileira de Ciencias
Base de datos: PERIÓDICA
Número de sistema: 000419770
ISSN: 0001-3765
Autores: 1
1
1
2
1
1
Instituciones: 1Universidade de Aveiro, Departamento de Quimica, Aveiro. Portugal
2Universidade de Aveiro, Departamento de Ciencias Biomedicas, Aveiro. Portugal
Año:
Periodo: May
Volumen: 90
Número: 1
Paginación: 1101-1130
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment
Disciplinas: Medicina,
Química
Palabras clave: Química farmacéutica,
Oncología,
Terapia fotodinámica,
Liberación de fármacos,
Liposomas,
Nanopartículas de sílice,
Nanopartículas de oro,
Micelas poliméricas
Keyword: Medicinal chemistry,
Oncology,
Photodynamic therapy,
Drug delivery,
Liposomes,
Silica nanoparticles,
Gold nanoparticles,
Polymeric micelles
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