| Journal: | Anais da Academia Brasileira de Ciencias |
| Database: | PERIÓDICA |
| System number: | 000436071 |
| ISSN: | 0001-3765 |
| Authors: | Mori, Marcelo A1 |
| Institutions: | 1Universidade Estadual de Campinas, Instituto de Biologia, Campinas, Sao Paulo. Brasil |
| Year: | 2020 |
| Volumen: | 92 |
| Number: | 2 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | The world is undergoing a profound demographic change with a rapid increase in the prevalence of aged individuals. The finitude of life, the burden of senescence and the search for strategies to prolong human life span have troubled humanity since ancient times. However, only in the past few decades we started to understand how organisms age and how life span can be manipulated. Here I give an historical perspective of the aging field and conclude with the notion that aging is controlled by signals from the adipose tissue which are tightly controlled by small non-coding RNAs such as miRNAs |
| Disciplines: | Medicina |
| Keyword: | Geriatría, Fisiología celular, Envejecimiento, Tejido adiposo, ARN mitocondrial, Longevidad, Biogénesis |
| Keyword: | Geriatrics, Cell physiology, Aging, Adipose tissue, Mitochondrial RNA, Longevity, Biogenesis |
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