| Journal: | Anais brasileiros de dermatologia |
| Database: | PERIÓDICA |
| System number: | 000425690 |
| ISSN: | 0365-0596 |
| Authors: | Merlotto, Maira Renata1 Cantadori, Lucas Oliveira1 Sakabe, Delmo2 Miot, Helio Amante1 |
| Institutions: | 1Universidade Estadual Paulista "Julio de Mesquita Filho", Faculdade de Medicina de Botucatu, Botucatu, Sao Paulo. Brasil 2Pontificia Universidade Catolica de Sao Paulo, Departamento de Cirurgia, Sao Paulo. Brasil |
| Year: | 2018 |
| Season: | May-Jun |
| Volumen: | 93 |
| Number: | 3 |
| Pages: | 451-453 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | Hypereosinophilic syndrome is defined as persistent eosinophilia (>1500/µL for more than six months) associated with organ involvement, excluding secondary causes. It is a rare, potentially lethal disease that should be considered in cutaneous conditions associated with hypereosinophilia. We report a case of erythroderma as a manifestation of hypereosinophilic syndrome. A 36-year-old male with no comorbidities presented progressive erythroderma, pruritus, peripheral neuropathy, and eosinophilia in the previous seven months. No mutations were found in FIP1L1/PDGFRA. Patient experienced rapid remission in response to oral prednisone and hydroxyurea. Cutaneous manifestations may be the only evidence of hypereosinophilic syndrome. Genotyping excludes myeloproliferative disease, thereby orienting treatment and prognosis |
| Disciplines: | Medicina |
| Keyword: | Dermatología, Diagnóstico diferencial, Eritrodermia, Eosinofilia, Síndrome hipereosinofílico, Dermatitis exfoliativa, Polineuropatías |
| Keyword: | Dermatology, Differential diagnosis, Erythrodermia, Eosinophilia, Hypereosinophilic syndrome, Exfoliative dermatitis, Polyneuropathies |
| Full text: | Texto completo (Ver HTML) |
