| Journal: | Anais brasileiros de dermatologia |
| Database: | PERIÓDICA |
| System number: | 000415209 |
| ISSN: | 0365-0596 |
| Authors: | Ding, Shu1 Deng, Qiancheng1 Xiang, Yaping1 Chen, Jing1 Huang, Jinhua1 Lu, Jianyun1 |
| Institutions: | 1Central South University, Third Xiangya Hospital, Changsha, Hunan. China |
| Year: | 2017 |
| Season: | Sep-Oct |
| Volumen: | 92 |
| Number: | 5 |
| Pages: | 120-122 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, descriptivo |
| English abstract | Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3). Coexistence of autoantibodies of bullous pemphigoid and pemphigus in a patient is rare. A 25-year-old male patient was admitted to our hospital, reporting a 3-month history of multiple papules, vesicles, and erosions over an extensive erythema on the entire body. Laboratory tests showed high levels of serum IgE, anti-BP180 antibodies, and anti-desmoglein 1 and 3. Histopathologic and immunopathologic features were characterized by bullous pemphigoid. No improvement was seen with systemic corticosteroid therapy, however, pulse corticosteriod therapy combined with methylprednisolone, immunosuppressants, immunomodulators, and plasmapheresis led to the recovery of his condition with numerous milia |
| Disciplines: | Medicina |
| Keyword: | Dermatología, Terapéutica y rehabilitación, Penfigoide ampollar, IgE, Miliaria, Desmogleína |
| Keyword: | Medicine, Dermatology, Therapeutics and rehabilitation, Bullous pemphigoid, IgE, Miliaria, Desmoglein |
| Full text: | Texto completo (Ver HTML) |
