| Revista: | Anais brasileiros de dermatologia |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000415209 |
| ISSN: | 0365-0596 |
| Autores: | Ding, Shu1 Deng, Qiancheng1 Xiang, Yaping1 Chen, Jing1 Huang, Jinhua1 Lu, Jianyun1 |
| Instituciones: | 1Central South University, Third Xiangya Hospital, Changsha, Hunan. China |
| Año: | 2017 |
| Periodo: | Sep-Oct |
| Volumen: | 92 |
| Número: | 5 |
| Paginación: | 120-122 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, descriptivo |
| Resumen en inglés | Bullous pemphigoid is a blistering autoimmune disease characterized by two hemidesmosomal proteins (anti-BP180 and 230). Pemphigus, by contrast, is characterized by two autoantibodies (anti-desmoglein 1 and 3). Coexistence of autoantibodies of bullous pemphigoid and pemphigus in a patient is rare. A 25-year-old male patient was admitted to our hospital, reporting a 3-month history of multiple papules, vesicles, and erosions over an extensive erythema on the entire body. Laboratory tests showed high levels of serum IgE, anti-BP180 antibodies, and anti-desmoglein 1 and 3. Histopathologic and immunopathologic features were characterized by bullous pemphigoid. No improvement was seen with systemic corticosteroid therapy, however, pulse corticosteriod therapy combined with methylprednisolone, immunosuppressants, immunomodulators, and plasmapheresis led to the recovery of his condition with numerous milia |
| Disciplinas: | Medicina |
| Palabras clave: | Dermatología, Terapéutica y rehabilitación, Penfigoide ampollar, IgE, Miliaria, Desmogleína |
| Keyword: | Medicine, Dermatology, Therapeutics and rehabilitation, Bullous pemphigoid, IgE, Miliaria, Desmoglein |
| Texto completo: | Texto completo (Ver HTML) |
