| Journal: | Acta ortopedica brasileira |
| Database: | PERIÓDICA |
| System number: | 000273595 |
| ISSN: | 1413-7852 |
| Authors: | Matos, Marcos Almeida1 Pimentel, Nilma Leite, Alexandre Alves2 |
| Institutions: | 1Escola Bahiana de Medicina e Saude Publica, Salvador, Bahia. Brasil 2Santa Casa de Misericordia da Bahia, Hospital Santa Izabel, Salvador, Bahia. Brasil |
| Year: | 2002 |
| Season: | Jul-Sep |
| Volumen: | 10 |
| Number: | 3 |
| Pages: | 9-14 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | From 1995 to 1998, twenty seven pediatric patients were included in a prospective clinical study. Their age ranging from 8.9 to 17.5 years old (mean 13.5), 20 (74%) were male and 7(26%) female, with a follow-up going from 3 to 39 months (average of 17). Osteogenic sarcoma arises in Knee (55.5%), ankle (26%), shoulder (11.1%), pelvis (3.7%) and hip (3.7%). Tumors less than 12cm were considered being small ones, while those bigger than 12cm were considered large. .All patients were submitted to clinical, radiological, histological evaluation and graded by Enneking(5) system (13 were IIB and 8 were IIIB); treated by chemotherapeutic agents, according to "Brazillian Protocol 91" and had a local surgical control. There were carried out 9 (42.9%) radical surgical interventions and 12 (57.1%) surgeries of limb preservation. According to lesion size, eight (38.1%) out of 14 (67.9%) patients with a tumor greater than 12cm died; in contrast, none out of 7 with tumor less than 12cm relapsed or died. Authors have concluded that tumor size can be a good factor for prognosis indication, being low cost, simple, easy to reproduce and specially useful for taking pre-treatmente decisions |
| Portuguese abstract | Entre 1995 a 1998, vinte e sete pacientes foram incluídos neste estudo clínico prospectivo. A idade variou entre 8,9 e 17,5 anos (média de 13,5), 20 (74%) eram do sexo masculino e 7 (26%) do sexo feminino com seguimento entre 3 e 39 meses (média de 17). O osteossarcoma incidiu no joelho (55,5%), tornozelo (26%), ombro (11,1%0), pelve (3,7%) e quadril (3,7%). Tumores menores que 12cm eram considerados pequenos e maiores que 12cm eram considerados grandes. Os pacientes foram submetidos a avaliação clínica, radiológica e histológica e classificados pelo sistema de Enneking(5) (13 eram IIB e 8 eram IIIB); foram tratados com agentes quimioterápicos de acordo com o protocolo brasileiro 91 e pelo controle cirúrgico local. Foram realizadas 9 (42,9%) cirurgias radicais e 12 (57,1%) cirurgias de preservação do membro. De acordo com o tamanho tumoral, 8 (38,1%) dos 14 (67,9%) pacientes com tumores maiores que 12cm faleceram; ao contrário, nenhum dos 7 pacientes com tumores menores que 12cm apresentaram recidiva ou faleceram. Os autores concluem que a medida do tamanho tumoral pode vir a ser um bom fator prognóstico, sendo também de baixo custo, simples, de fácil reprodutibilidade e especialmente útil para tomada de decisões pré-tratamento |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Oncología, Traumatología y ortopedia, Osteosarcoma, Prognosis, Quimioterapia, Resección quirúrgica |
| Keyword: | Medicine, Diagnosis, Oncology, Traumatology and orthopedics, Osteosarcoma, Prognosis, Chemotherapy, Surgical resection |
| Full text: | Texto completo (Ver HTML) |
