Analysis of the interface formed among the poli (viniilidene) fluoride (piezoelectric and non-piezoelectric) and the bone tissue of rats



Document title: Analysis of the interface formed among the poli (viniilidene) fluoride (piezoelectric and non-piezoelectric) and the bone tissue of rats
Journal: Acta ortopedica brasileira
Database: PERIÓDICA
System number: 000266417
ISSN: 1413-7852
Authors: 1
Institutions: 1Universidade Estadual de Campinas, Faculdade de Ciencias Medicas, Campinas, Sao Paulo. Brasil
Year:
Season: Jul-Sep
Volumen: 12
Number: 3
Country: Brasil
Language: Portugués, inglés
Document type: Artículo
Approach: Experimental, analítico
English abstract The objective of this study was to evaluate the interface formed between the poli (viniilidene) fluoride (PVDF-piezoelectric and non-piezoelectric) and cap rats' bone tissue. Twenty tubes of PVDF [P (VDF-TrFE)] piezoelectric, (d3h = 2,5 pC/N and capacitance 800 pF/m), and twenty tubes of non-piezoelectric PVDF were implanted in the intercondilian notch of the left femur of 40 rats. The animals of both groups were subdivided in four subgroups, followed up for 7 days, 3, 6 and 12 weeks. The interface found between bone and tubes was studied by conventional optical microscopy (MOC) (n=28) and by backscattered electronic scanning microscopy (MEV) (n=12). Bone tissue growth was observed inside the tubes of piezoelectric PVDF followed up during 12 weeks, both by MOC and by MEV backscattering. The results indicate that the piezoelectric effect had an important role in the new bone tissue formation inside the piezoelectric tubes. Probably, that bone formation was a result from the electrets effect or from micro deformations produced in the piezoelectric tubes, due to the intra-articular pressure variation on the knee movement during gait
Portuguese abstract O objetivo deste estudo foi analisar a interface formada entre o polifluoreto de vinilideno (PVDF - piezelétrico e não piezelétrico) e o tecido ósseo do rato. Foram implantados em 40 ratos, na região intercondiliana do fêmur esquerdo, vinte tubos de PVDF [P(VDF-TrFE)] piezelétricos, (d3h = 2,5 pC/N e capacitância 800 pF/m), e vinte tubos de PVDF não piezelétricos. Os animais de ambos os grupos foram subdivididos em quatro subgrupos, seguidos por 7 dias, 3, 6 e 12 semanas. A interface formada pelos tubos com o tecido ósseo foi estudada por microscopia óptica convencional (MOC) (n=28) e pela microscopia eletrônica de varredura (MEV) por retroespalhamento (n=12). No interior dos tubos de PVDF piezelétricos seguidos por 12 semanas foi constatado, tanto pela MOC como pela MEV por retroespalhamento, crescimento de tecido ósseo. Os resultados indicam que a piezeletricidade teve papel importante na neoformação do tecido ósseo no interior dos tubos piezelétricos. Provavelmente, essa formação óssea foi decorrente ou do efeito eletreto, ou das microdeformações produzidas nos tubos piezelétricos, devido à variação da pressão intra articular do joelho durante a marcha
Disciplines: Medicina,
Biología
Keyword: Medicina experimental,
Traumatología y ortopedia,
Biología celular,
Piezoelectricidad,
Huesos,
Crecimiento,
Implantes,
Histología,
Osteogénesis,
Biomateriales
Keyword: Medicine,
Biology,
Experimental medicine,
Traumatology and orthopedics,
Cell biology,
Piezoelectricity,
Bones,
Growth,
Implants,
Histology,
Osteogenesis,
Biomaterials
Full text: Texto completo (Ver HTML)