| Revue: | The brazilian journal of infectious diseases |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000290840 |
| ISSN: | 1413-8670 |
| Autores: | Mendes, Caio1 Kiffer, Carlos2 Segura, Adilia3 Ribeiro, Julival Turner, Philip4 |
| Instituciones: | 1Universidade de Sao Paulo, Sao Paulo. Brasil 2Fleury Medicina e Saude, Grupo Consultivo para a Antimicrobianos e Microbiologia Clinica, Sao Paulo. Brasil 3Hospital de Base de Brasilia, Brasilia, Distrito Federal. Brasil 4Antrazeneca Macclesfield, Cheshire. Reino Unido |
| Año: | 2004 |
| Periodo: | Feb |
| Volumen: | 8 |
| Número: | 1 |
| Paginación: | 109-111 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | A Klebsiella pneumoniae strain was isolated from the urine of a patient at one of the centers participating in the 2001 edition of the MYSTIC program in Brazil. The initial phenotypic findings of the isolated K. pneumoniae presented an unusual MIC of 8 mg/mL to meropenem, 2 mg/mL to imipenem, elevated MICs to broad spectrum cephalosporins (ceftazidime/cefotaxime/cefepime MIC > 256 mg/mL), aminoglycosides (gentamycin > 256 mg/mL and tobramycin = 48 mg/mL), piperacillin/tazobactam (MIC > 256 mg/mL) and susceptibility to ciprofloxacin (MIC = 0.25 mg/mL). The strain also tested positive for ESBL production with double-disk and E-test methodologies. More detailed investigation revealed that the strain produced a SHV-4 type enzyme and also lacked a 36 kDa outer membrane porin |
| Disciplinas: | Medicina |
| Palabras clave: | Farmacología, Microbiología, Klebsiella pneumoniae, Medicamentos, Resistencia, Carbapenemas |
| Keyword: | Medicine, Microbiology, Pharmacology, Klebsiella pneumoniae, Drugs, Resistance, Carbapenems |
| Texte intégral: | Texto completo (Ver HTML) |
