| Revista: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000321357 |
| ISSN: | 0034-9887 |
| Autores: | Márquez, Sonia1 Peredo, María Soledad1 Vogel, Andrea1 Ibáñez, Paulina1 |
| Instituciones: | 1Pontificia Universidad Católica de Chile, Facultad de Medicina, Santiago de Chile. Chile |
| Año: | 2009 |
| Periodo: | Mar |
| Volumen: | 137 |
| Número: | 3 |
| Paginación: | 405-410 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2%-4%. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV). They are more common in younger children, EBV seronegative patients and those who receive aggressive immunosuppression. PTLD commonly presents in an unspecific form and it requires high suspicion rate for its diagnosis, especially in children with risk factors. We report a twelve year-old girl who developed fever, sore throat and lymph node enlargement, six months after receiving a renal allograft. Laboratory assessment and imaging studies were compatible with PTLD, which was confirmed by biopsy. Treatment was reduction of immunosuppression and surveillance. The patient had a favorable evolution |
| Disciplinas: | Medicina |
| Palabras clave: | Nefrología, Pediatría, Inmunología, Síndromes linfoproliferativos, Trasplantes, Riñones, Inmunosupresión |
| Keyword: | Medicine, Nephrology, Pediatrics, Lymphoproliferative syndromes, Transplantation, Kidneys, Immunosuppression, Immunology |
| Texto completo: | Texto completo (Ver HTML) |
