Updating Zika Diagnostic Methods: The Point-of-Care Approach



Título del documento: Updating Zika Diagnostic Methods: The Point-of-Care Approach
Revue: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000453194
ISSN: 0034-8376
Autores: 1
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Instituciones: 1Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A.C., Unidad de Biotecnología Médica y Farmacéutica, Guadalajara, Jalisco. México
Año:
Periodo: Nov-Dic
Volumen: 72
Número: 6
Paginación: 344-352
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Zika virus (ZIKV) has gained great importance worldwide since the past epidemic that occurred in 2015 in Brazil. Early identification of ZIKV is critical to minimize transmission and prevents potentially devastating consequences, including microcephaly in neonates of infected women, congenital blindness, or Guillain-Barré Syndrome. However, this is not an easy task, considering that approximately 80% of ZIKV infection cases are asymptomatic or oligosymptomatic, there are diverse modes of transmission (vertical transmission is through vectors and horizontal transmission through blood, saliva, semen, and urine from infected people), and the fact that ZIKV has a high identity percentage with other cocirculating Flaviviruses such as dengue. Here, we review ZIKV diagnostic methods, with special emphasis on the development of point-of-care diagnostic assays, since these devices commonly have two important advantages: they provide prompt screening and are affordable
Disciplinas: Medicina
Palabras clave: Virus,
Diagnóstico,
Flavivirus,
Virus del Zika,
Técnicas de diagnóstico
Keyword: Virus,
Diagnosis,
Flavivirus,
Zika virus,
Diagnostic techniques
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