Screening Tool for Restrictive and Obstructive Ventilatory Abnormalities in a Population-Based Survey



Título del documento: Screening Tool for Restrictive and Obstructive Ventilatory Abnormalities in a Population-Based Survey
Revue: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000453187
ISSN: 0034-8376
Autores: 1
2
1
1
2
Instituciones: 1Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Departamento de Epidemiología, Ciudad de México. México
2Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Departamento de Investigación en Tabaquismo y EPOC, Ciudad de México. México
Año:
Periodo: Nov-Dic
Volumen: 72
Número: 6
Paginación: 386-393
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Background: A 6 s spirometry with an inexpensive pocket spirometer efficiently selects individuals for a diagnostic-quality spirometry for airflow limitation, but could also be useful to identify individuals with a restrictive pattern. Objectives: We evaluated an inexpensive simplified spirometer (chronic obstructive pulmonary disease [COPD]-6) as a screening tool to identify spirometric abnormalities. Methods: A population-based survey in Mexico City, with 742 participants performing pre- and post-BD spirometry and a three-maneuver 6 s spirometry (pre-BD) with a COPD-6. We evaluated forced expiratory volume in 1 s (FEV1), FEV6, and FEV1/FEV6 from the COPD-6, crude and expressed as the percentage of predicted (%P), to discriminate post-bronchodilator airflow obstruction (FEV1/forced vital capacity [FVC] <5th percentile) or restriction (FVC or FEV1 <5th percentile with normal FEV1/FVC) through receiver operating characteristics and their area under the curve (AUC). Results: FEV1%P was the best predictor to identify pre- and post-BD ventilatory abnormalities (best cutoff point 87%P, AUC 92% for restrictive pattern, 89% for obstructive pattern, and 91% for any spirometric abnormality). Deriving to clinical spirometry only those with <87%P (26% of the sample) missed only 12% of spirometric abnormalities most of the latter mild. Conclusions: An FEV1 <87%P from a pre-BD 6 s spirometry correctly identified individuals with spirometric ventilatory defects, either obstructive or restrictive
Disciplinas: Medicina
Palabras clave: Neumología,
Diagnóstico,
Enfermedad pulmonar obstructiva crónica (EPOC),
Volumen expiratorio,
Espirometría
Keyword: Pneumology,
Diagnosis,
Chronic obstructive pulmonary disease (COPD),
Expiratory volume,
Spirometry
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