| Revista: | Nutrire |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000333524 |
| ISSN: | 1519-8928 |
| Autores: | Fujii, Tatiane Mieko de Meneses1 Yamada, Ruth1 Medeiros, Roberta de1 |
| Instituciones: | 1Centro Universitario Sao Camilo, Sao Paulo. Brasil |
| Año: | 2010 |
| Periodo: | Abr |
| Volumen: | 35 |
| Número: | 1 |
| Paginación: | 149-166 |
| País: | Brasil |
| Idioma: | Portugués |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico |
| Resumen en español | El desafío es entender como esa interacción infl uye en el equilibrio entre salud y enfermedad. Tal conocimiento permitirá al profesional de nutrición una intervención nutricional efi caz una vez que el mismo tendrá como base los datos del mapa genético de su cliente |
| Resumen en inglés | The genetic map accomplished in the Human Genome Project was crucial to supply the tools and information about genetic aspects. The knowledge about the communication between genes and food compounds, such as nutrients and bioactive compounds, enabled the emergence of two new sciences, named nutrigenomics and nutrigenetics. Nutrigenomics refers to the study of how these compounds can act in the genetic expression modulation, while nutrigenetics studies the effect of genetic variation in the diet and disease interaction, with the identifi cation of genes responsible for different responses to diet. Given the importance of understanding the interaction between diet and gene, whereas the substances found in food can modify phenotype, the purpose of the present work is to search and gather literature data about the main advances in nutrigenomics and nutrigenetics, thus contributing to the updated education of students and health professionals. In order to achieve it, an extensive bibliographic research was done into the main scientifi c electronic database Pubmed and Medline, using the descriptors Nutrigenomics, Nutritional Genomics, Nutrigenetics. Data observed in literature state that environmental factors, mainly the diet, can initiate different responses among individuals due to genetic variability or polymorphisms. The current technology allows the identifi cation of more than 500 thousand polymorphisms per person. However, only some of them seem to have functional effect. In epigenetic events, polymorphisms are responsible for modifying the phenotype and even for the function of genes, resulting in metabolic changes such as increase or decrease in dietary intake requirements. So, the challenge is to understand how this interaction works on the balance between health and disease. This knowledge will allow an effective nutritional intervention by the professional, based on the client’s genetic map |
| Resumen en portugués | Tal conhecimento poderá possibilitar ao profi ssional de nutrição uma efi caz intervenção nutricional, uma vez que o mesmo terá como base os dados do mapa genético individual de seu cliente |
| Disciplinas: | Medicina |
| Palabras clave: | Metabolismo y nutrición, Genética, Nutrigenómica, Nutrigenética, Polimorfismo genético, Mapa genético |
| Keyword: | Medicine, Metabolism and nutrition, Genetics, Nutrigenomics, Nutrigenetics, Genetic polymorphism, Genetic mapping |
| Solicitud del documento | |
