| Revue: | Memorias do Instituto Oswaldo Cruz |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000420020 |
| ISSN: | 0074-0276 |
| Autores: | Silva, Marcio Roberto1 Rocha, Adalgiza da Silva2 Araújo, Flábio Ribeiro3 Fonseca-Júnior, Antônio Augusto4 Alencar, Andrea Padilha de4 Suffys, Philip Noel2 Costa, Ronaldo Rodrigues da5 Moreira, Maria Aparecida Scatamburlo6 Guimarães, Mark Drew Crosland7 |
| Instituciones: | 1Empresa Brasileira de Pesquisa Agropecuaria, Gado de Leite, Juiz de Fora, Minas Gerais. Brasil 2Fundacao Oswaldo Cruz, Rio de Janeiro. Brasil 3Empresa Brasileira de Pesquisa Agropecuaria, Gado de Corte, Campo Grande, Mato Grosso do Sul. Brasil 4Ministerio da Agricultura, Pecuaria e Abastecimento, Pedro Leopoldo, Minas Gerais. Brasil 5Hospital Regional Joao Penido, Juiz de Fora, Minas Gerais. Brasil 6Universidade Federal de Vicosa, Vicosa, Minas Gerais. Brasil 7Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais. Brasil |
| Año: | 2018 |
| Volumen: | 113 |
| Número: | 8 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | The World Health Organization (WHO) has classified human zoonotic tuberculosis (TB) due to Mycobacterium bovis as a neglected issue in the developing world. In a recent cross-sectional study in Brazil, three of 189 TB patients presented with a coinfection of M. bovis and M. tuberculosis and were selected as cases for this study. OBJECTIVE The aim was to evaluate risk factors (RF) for zoonotic TB in an urban area of Brazil in order to guide preventive programmes. METHODS A matched case-control study was carried out nested within a cross-sectional study. For each of the three cases, 14 age- and sex-matched controls (TB due to M. tuberculosis) were selected. FINDINGS Zoonotic potential exposures (ZE) and extrapulmonary TB (EPTB) were independently associated with zoonotic TB in multivariate analyses. CONCLUSIONS ZE by occupation and consumption of raw milk and derivative products that place individuals in direct and indirect contact with animals and their excretions/secretions increase the risk for zoonotic TB in Brazil, especially among those with EPTB. Therefore, measures such as efficient control of bovine TB, distribution of pasteurised milk and its derivative products, and the diagnosis and monitoring of zoonotic TB in humans are essential steps, especially in developing countries where bovine TB is enzootic, and further studies are necessary |
| Disciplinas: | Medicina |
| Palabras clave: | Microbiología, Salud pública, Zoonosis, Tuberculosis, Factores de riesgo, Areas urbanas, Mycobacterium bovis |
| Keyword: | Microbiology, Public health, Zoonoses, Tuberculosis, Risk factors, Urban areas, Mycobacterium bovis |
| Texte intégral: | Texto completo (Ver HTML) |
