The PROMISE-V2 PRIMARY score and SULmax [18F]PSMA-1007 PET/CT in primary staging of prostate cancer



Título del documento: The PROMISE-V2 PRIMARY score and SULmax [18F]PSMA-1007 PET/CT in primary staging of prostate cancer
Revista: Journal of the Mexican Federation of Radiology and Imaging
Base de datos:
Número de sistema: 000606790
ISSN: 2696-8444
Autores: 1
2
3
4
4
Instituciones: 1Hospital Angeles del Pedregal, Servicio de Radiología e Imagen, Ciudad de México. México
2Centro de Imagen y Diagnóstico, Departamento de Imagen Molecular PET/CT, Guadalajara, Jalisco. México
3Petróleos Mexicanos, Hospital Central del Sur de Alta Especialidad, Ciudad de México. México
4Universidad Autónoma Metropolitana, Departamento de Atención a la Salud, Xochimilco, Ciudad de México. México
Año:
Periodo: Ene-Mar
Volumen: 3
Número: 4
Paginación: 243-255
País: México
Idioma: Inglés
Tipo de documento: Artículo
Resumen en inglés Introduction: The PRIMARY score of the PROMISE-V2 criteria for primary staging of prostate cancer (PCa) and its relationship with the maximum standardized uptake value normalized to lean body mass (SULmax) have not been evaluated. This study determined the relationship between the SULmax value in [18F]PSMA-1007 PET/CT and the PROMISE-V2 PRIMARY score in patients with untreated PCa in primary staging. Material and Methods: This cross-sectional study included patients with PCa in primary staging. The SULmax value [18F]PSMA-1007 PET/CT of the intraprostatic lesion was recorded, and the PRIMARY score was assessed based on the pattern of affected prostate zones (peripheral, transitional, or central) and the distribution of prostate-specific membrane antigen (PSMA) uptake (focal or diffuse). Lymph node (pelvic or extrapelvic) spread and metastasis (bone, lung, and/ or brain) were determined. Results: Fifty-five patients with PCa at primary staging were included. The SULmax value of an intraprostatic tumor in PRIMARY score 2 was 5.15 ± 0.54 g/mL; in PRIMARY score 3, 7.11 g/mL; in PRIMARY score 4, 8.31 ± 1.92 g/mL, and in PRIMARY score 5, 22.64 ± 7.77 (p 12 g/mL. The expression of PSMA uptake in the local tumor was highest in the pattern of focal involvement in the peripheral zone (PZ) as long as the disease was confined to the pelvis.
Disciplinas: Medicina,
Medicina
Palabras clave: Oncología,
Diagnóstico
Keyword: Oncology,
Diagnosis
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