| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434695 |
| ISSN: | 1677-5538 |
| Autores: | Haghmorad, Dariush1 Mahmoudi, Mohammad Bagher2 Haghighi, Pardis3 Alidadiani, Paria3 Shahvazian, Ensieh3 Tavasolian, Parsova3 Hosseini, Mahmoud3 Mahmoudi, Mahmoud3 |
| Instituciones: | 1Semnan University of Medical Sciences, School of Medicine, Semnan. Irán 2Shahid Sadoughi University of Medical Sciences, Department of Genetics, Yazd. Irán 3Mashhad University of Medical Sciences, School of Medicine, Mashad. Irán |
| Año: | 2019 |
| Periodo: | Sep-Dic |
| Volumen: | 45 |
| Número: | 5 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Objective Anacyclus Pyrethrum (AP) and Tribulus Terrestris (TT) have been reported as male infertility treatment in several studies; however, in Iranian traditional medicine these two plants are prescribed simultaneously. In this study, we aimed to determine the effects of AP and TT extracts both separately and simultaneously on the male Wistar rat fertility parameters. Materials and Methods 32 male Wistar rats were divided into 4 groups: Control, TT, AP, and AT treated groups. Treatment continued for 25 days and rats were weighed daily. Their testes were dissected for histological studies. Sperm analysis including sperm count, viability and motility were performed. Serum was obtained to evaluate testosterone, LH and FSH levels. Histological studies were conducted to study Leydig, and Sertoli cells, spermatogonia and spermatid cell numbers, and to measure seminiferous diameter and epithelium thickness. Results Sperm count increased in all the treatment groups. Sperm viability and motility in AT and AP groups were elevated. TT and AT groups showed significantly increased testosterone level compared to control group (P=004, P=0.000, respectively) and TT, AP and AT treatment groups showed increased LH level (P=0.002, P=0.03 and P=0.000, respectively) compared to control, while only AT group showed increased FSH (p=0.006) compared to control. Histological studies showed significant increase of spermatogonia, Leydig and Sertoli cell numbers and epithelial thickness in AT group compared to other groups. All the treatment groups had higher number of Leydig, spermatogonia and spermatid cells. Conclusion TT and AP improved sexual parameters; however, their simultaneous administration had higher improving effects on studied parameters |
| Disciplinas: | Medicina, Química |
| Palabras clave: | Fitoquímica, Medicina experimental, Reproducción y desarrollo, Fertilidad, Plantas medicinales, Receptores hormonales, Testosterona, FSH, LH, Anacyclus pyrethrum, Asteraceae, Tribulus terrestris, Zygophyllaceae |
| Keyword: | Phytochemistry, Experimental medicine, Reproduction and development, Fertility, Hormonal receptors, Testosterone, FSH, LH, Anacyclus pyrethrum, Asteraceae, Tribulus terrestris, Zygophyllaceae |
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