Assessment of urodynamic bladder behavior on filling with solutions representing physiological extremes of urinary osmolarity



Título del documento: Assessment of urodynamic bladder behavior on filling with solutions representing physiological extremes of urinary osmolarity
Revue: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000296722
ISSN: 1677-5538
Autores: 1


Instituciones: 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Ribeirao Preto, Sao Paulo. Brasil
Año:
Periodo: Nov-Dic
Volumen: 31
Número: 6
Paginación: 569-578
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, analítico
Resumen en inglés OBJECTIVE: Verify if there is any difference in sensitive and motor bladder response in the presence of solutions with different osmolarities, simulating physiological extremes of urinary osmolarity. MATERIALS AND METHODS: Thirty-three patients (24 men and 9 women) with mean age of 46.4 years (8 to 87 years) took part in this study. They were all subjected to 2 consecutive urodynamic examinations. In each exam, the vesical filling was accomplished by using a hyperosmolar (1000 mOsm/L) or hypo-osmolar (100 mOsm/L) sodium chloride solution in similar speed. The sequence in which each solution was instilled was determined by a double blind draw. The urodynamic results obtained from the infusion of both solutions were compared, regardless the sequence of administration. RESULTS: Fifteen patients (45.4%) showed detrusor hyperactivity, 12 of whom with neurological antecedents. The mean age of those with detrusor hyperactivity was 45.8 years, against 46.9 for those without hyperactivity. The infusion of the hyperosmolar/hypo-osmolar solution generated the following results, when comparing patients without vs. with detrusor hyperactivity: initial sensation of vesical filling (mL): 167.5 / 159.2 vs. 134.9 / 157.3 (p > 0.05); volume of occurrence of the first involuntary bladder contraction (mL): 163.9 / 151.9 (p > 0.05); detrusor micturition pressure (cm H2O): 24.0 / 24.4 vs. 13.8 / 27.5 (p > 0.05). CONCLUSION: The vesical filling with solutions simulating extreme urinary osmolarities, accomplished with similar speed
Disciplinas: Medicina
Palabras clave: Cirugía,
Vejiga,
Urodinámica,
Soluciones hipertónicas,
Soluciones hipotónicas,
Osmolaridad,
Orina
Keyword: Medicine,
Surgery,
Bladder,
Urodynamics,
Hypertonic solutions,
Hypotonic solutions,
Osmolarity,
Urine
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