| Revue: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000296438 |
| ISSN: | 1677-5538 |
| Autores: | Tobias-Machado, M1 Correa, Thiago D Barros, Emilia L de Wroclawski, Eric R |
| Instituciones: | 1Faculdade de Medicina do ABC, Disciplina de Urologia, Santo Andre, Sao Paulo. Brasil |
| Año: | 2003 |
| Periodo: | Jul-Ago |
| Volumen: | 29 |
| Número: | 4 |
| Paginación: | 313-319 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico, analítico |
| Resumen en inglés | OBJECTIVE: To compare, prospectively, 4 different schemes of antibiotic prophylaxis previously to transrectal prostate biopsy. MATERIALS AND METHODS: 257 patients were randomized in 4 groups: Group I: single dose of ciprofloxacin 2 hours before the procedure; Group II: ciprofloxacin 3 days; Group III: chloramphenicol 3 days; and Group IV: norfloxacin 3 days. The complication rate was assessed in a blind way on the third and on the thirtieth days through a questionnaire. Groups were compared by the qui-square method and, in small samples, by the Fisher method, with statistical significance of 95%. RESULTS: Complications index throughout the sample differed between the 4 groups of patients under study, being 3.1% for group I, 2.1% for group II, 18.3% for group III and 10.5% for group IV. Schemes employing ciprofloxacin were statistically superior to those that used norfloxacin or chloramphenicol (p < 0.05). There was no difference between a single dose and 3 days of ciprofloxacin (p > 0.05). CONCLUSION: Schemes using ciprofloxacin presented better results in prophylaxis previously to prostate biopsy. We recommend using a single dose of ciprofloxacin due to its posologic ease and low cost, associated with a therapeutic response equivalent to 3-day regimens |
| Disciplinas: | Medicina |
| Palabras clave: | Cirugía, Terapéutica y rehabilitación, Próstata, Biopsia, Profilaxis, Ultrasonografía, Antibióticos |
| Keyword: | Medicine, Surgery, Therapeutics and rehabilitation, Prostate, Biopsy, Prophylaxis, Ultrasonography, Antibiotics |
| Texte intégral: | Texto completo (Ver HTML) |
