| Revue: | Genetics and molecular biology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000459286 |
| ISSN: | 1415-4757 |
| Autores: | Lima Noronha, Marco A1 Fonseca, Douglas L.H1 Oliveira, Renatta S1 Freitas, Rúbia R1 Park, Jung H1 Galhardo, Rodrigo S1 |
| Instituciones: | 1Universidade de Sao Paulo, Instituto de Ciencias Biomedicas, Sao Paulo. Brasil |
| Año: | 2022 |
| Volumen: | 45 |
| Número: | 3 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Descriptivo |
| Resumen en inglés | The term “SOS response” was first coined by Radman in 1974, in an intellectual effort to put together the data suggestive of a concerted gene expression program in cells undergoing DNA damage. A large amount of information about this cellular response has been collected over the following decades. In this review, we will focus on a few of the relevant aspects about the SOS response: its mechanism of control and the stressors which activate it, the diversity of regulated genes in different species, its role in mutagenesis and evolution including the development of antimicrobial resistance, and its relationship with mobile genetic elements |
| Disciplinas: | Biología |
| Palabras clave: | Bacterias, Genética, Envío de un SOS: la respuesta al daño del, ADN, Daño, Mutagenesis, Polimerasas, TLS, Revisión bibliográfica |
| Keyword: | DNA, Damage, Mutagenesis, Polymerases, TLS, Bibliographic review |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
