| Revue: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000452203 |
| ISSN: | 1984-8250 |
| Autores: | Sethi, Sonali1 Prakash, Om1 Kumar, Ravendra1 Dubey, Shiv Kumar1 Arya, Mamta2 Pant, Anil Kumar1 |
| Instituciones: | 1G.B. Pant University of Agriculture and Technology, College of Basic Sciences and Humanities, Pantnagar, Uttarakhand. India 2H.N.B. Garhwal University, Department of Biotechnology, Srinagar, Uttarakhand. India |
| Año: | 2022 |
| Volumen: | 58 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | The present study describes chemical composition, phytochemicals, antifungal activities, antioxidant assays and total phenolic content of essential oil and varied polarity solvent extract from flowers of Alpinia malaccensis (Burm.f.). Total 27 components were identified in essential oil by GC-MS with terpinen-4-ol (28.6%) and α- terpineol (12.8%) as the main constituent. The essential oil was found to have maximal levels of phenolic content (64.60 μg/mL) as compared to the other extracts. The antioxidant assay evaluated in extracts and essential oil by different methods revealed good-to-moderate antioxidant potential with different IC50 values viz. (188.02 -250.25 μg/mL) in Fe3+ reducing power, (153.15-201.59 μg/mL) in Fe2+ metal-chelating ability, (130.39-181.12 μg/mL) in DPPH, (88.29-187.32 μg/mL) in OH radical, (79.04-156.79 μg/mL), in NO radical and (138.72-233.00 μg/mL) in superoxide anion scavenging activities, respectively. The methanolic extract display remarkable fungicidal activity against the tested pathogens followed by dichloromethane extract, essential oil, hexane extract and petroleum ether extract respectively, with MIC values ranging from 31.25 to 500 μg/mL. Based on results, it can be inferred that the flower of A. malaccensis if explored further for its medicinal properties, might be a good source to develop a safe and sustainable natural food preservative |
| Disciplinas: | Biología, Química |
| Palabras clave: | Angiospermas, Fitoquímica, Compuestos fenólicos, Actividad antifúngica, Actividad antioxidante, Alpinia malaccensis, Zingiberaceae |
| Keyword: | Angiosperms, Phytochemistry, Phenolic compounds, Antifungal activity, Antioxidant activity, Alpinia malaccensis, Zingiberaceae |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
