| Revue: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000451088 |
| ISSN: | 1984-8250 |
| Autores: | Lavaee, Fatemeh1 Moshaverinia, Maryam1 MalekHosseini, Seyed Ali2 Jamshidzade, Akram3 Zarei, Maryam1 Jafarian, Hadis4 Haddadi, Pardis5 Badiee, Parisa4 |
| Instituciones: | 1Shiraz University of Medical Sciences, Oral and Dental Disease Research Center, Shiraz. Irán 2Shiraz University of Medical Sciences, Transplant Research Center, Shiraz. Irán 3Shiraz University of Medical Sciences, Pharmacology and Toxicology Department, Shiraz. Irán 4Shiraz University of Medical Sciences, Professor Alborzi Clinical Microbiology Research Center, Shiraz. Irán 5Lorestan University of Medical Sciences, Department of Periodontology, Khorramabad. Irán |
| Año: | 2019 |
| Volumen: | 55 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | The aim of this study was to evaluate the antifungal susceptibility patterns of three antifungals, methanolic extracts and N-hexane oil of sesame seeds on C. albicans and C. glabrata, isolated from oral cavity of liver transplant recipients. The results were compared with other reports to develop a mini review as well. Candida species were isolated from liver transplant recipients. To evaluate the antifungal activity of sesame seed oil and methanolic extract, fluconazole, caspofungin and nystatin, the corresponding minimum inhibitory concentrations were determined by CLSI M27-A3 standard method. Minimum fungicidal concentration was also evaluated. The most prevalent species was C. albicans, followed by C. glabrata. Findings indicated sensitivity to antifungal agents and resistance to methanolic extract and N-hexane oil for all C. albicans and C. glabrata isolates. The rate of Candida colonization in the oral cavity of liver transplant recipients was high. Our results revealed that the methanolic and N-hexan extracts of sesame seeds are not effective on C. albicans and C. glabrata species, isolated from the patients. The sesame seed oil pulling and mouthwash cannot effectively cleanse and remove the Candida species in the mouth. Investigation of other medicinal plants or other parts of sesame like leaves and roots are suggested |
| Disciplinas: | Química, Medicina |
| Palabras clave: | Farmacología, Microbiología, Antifúngicos, Plantas medicinales, Sésamo, Susceptibilidad, Candida |
| Keyword: | Pharmacology, Microbiology, Antifungal agents, Sesame, Susceptibility, Candida |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
