Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals



Título del documento: Genotypic diversity and virulence factors of Streptococcus mutans in caries-free and caries-active individuals
Revue: Brazilian archives of biology and technology
Base de datos: PERIÓDICA
Número de sistema: 000365565
ISSN: 1516-8913
Autores: 1
1
1
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2
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Instituciones: 1Universidade Norte do Parana, Londrina, Parana. Brasil
2Universidade de Sao Paulo, Faculdade de Odontologia de Bauru, Bauru, Sao Paulo. Brasil
Año:
Periodo: Mar-Abr
Volumen: 56
Número: 2
Paginación: 241-248
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés The objective of this study was to analyze the genotypic diversity, frequency of serotypes and the detection of mutacins from Streptococcus mutans isolates in caries-free and caries-active individuals.A total of 260 S. mutans isolated from 28 individuals with and without dental caries were subjected to AP-PCR and PCR screening of glucosyltransferase B, mutacin and serotype genes, which showed the presence of. 70 different genotypes. There was no statistically significant association between the presence of genes for serotypes and mutacins with dental caries. However, there was a statistically significant and a strong association between the higher genotypic diversity in the subjects with caries (r = 0.72, p = 0.001). There was an increase in the number of genotypes with increasing age (p <0.01)
Disciplinas: Medicina
Palabras clave: Microbiología,
Odontología,
Caries,
Serotipos,
Variabilidad genética,
Factores de virulencia,
Mutacina,
Streptococcus mutans
Keyword: Medicine,
Dentistry,
Microbiology,
Caries,
Serotypes,
Genetic variability,
Virulence factors,
Mutacin,
Streptococcus mutans
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