| Revue: | Brazilian archives of biology and technology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000387717 |
| ISSN: | 1516-8913 |
| Autores: | Oliveira, Gleidson Benevides de1 Vale, Andre Menezes do1 Santos, Amílton Cesar dos2 Moura, Carlos Eduardo Bezerra de1 Rocha, Hugo Alexandre de Oliveira3 Oliveira, Moacir Franco de1 |
| Instituciones: | 1Universidade Federal Rural do Semi-Arido, Departamento de Ciencias Animais, Mossoro, Rio Grande do Norte. Brasil 2Universidade de Sao Paulo, Faculdade de Medicina Veterinaria e Zootecnia, Sao Paulo. Brasil 3Universidade Federal do Rio Grande do Norte, Departamento de Bioquimica, Natal, Rio Grande do Norte. Brasil |
| Año: | 2015 |
| Periodo: | Jul-Ago |
| Volumen: | 58 |
| Número: | 4 |
| Paginación: | 512-520 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | Glycosaminoglycans (GAGs) are heteropolysaccharides in mammalian tissue and consist of repeated disaccharide units with mono-sulfated or non-sulfated monosaccharides. GAGs are important components of the Extracellular Matrix (ECM) with several physiological roles, in the recognition, migration, adhesion, proliferation and differentiation processes. They are also important in angiogenesis, blood homeostasis, immune reactions, follicule development and also in the development of pathologies such as infertility, tumors and metastases. It has been shown that the profile of glycosaminoglycans in the uterine and placental tissues is highly variable throughout the reproductive cycle and during pregnancy. It may be directly related to their physiological or pathological functions in the tissue. The latter has recently triggered special clinical interest. Current review collaborates for a deeper knowledge on the profile and importance of GAGs in uterine and placental tissues throughout the reproductive cycle and pregnancy. It also covers information on the involvement of these molecules in pathological processes |
| Disciplinas: | Biología |
| Palabras clave: | Mamíferos, Bioquímica, Glucosaminoglucanos, Matriz extracelular, Fluctuación hormonal, Eventos reproductivos, Placenta, Utero |
| Keyword: | Biology, Mammals, Biochemistry, Glycosaminoglycans, Extracellular matrix, Hormonal fluctuation, Reproductive events, Placenta, Uterus |
| Texte intégral: | Texto completo (Ver HTML) |
