| Revue: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000413455 |
| ISSN: | 1665-2681 |
| Autores: | Pinto, Felix P.D Ferreira-Junior, Orlando C1 Olmedo, Daniele B2 Precioso, Patricia M3 Barquette, Fernanda R.S2 Castilho, Magda C3 Silva, Suely G.C4 Porto, Luis Cristovao3 |
| Instituciones: | 1Universidade Federal do Rio de Janeiro, Instituto de Biologia, Rio de Janeiro. Brasil 2Policlinica Piquet Carneiro, Servico de Patologia Clinica, Rio de Janeiro. Brasil 3Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro. Brasil 4Instituto Nacional de Cancer Jose Alencar Gomes da Silva, Servico de Hemoterapia, Rio de Janeiro. Brasil |
| Año: | 2015 |
| Periodo: | Nov-Dic |
| Volumen: | 14 |
| Número: | 6 |
| Paginación: | 815-825 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Epidemics of hepatitis B and C are a public health burden, and their prevalence in Brazil varies among regions. We determined the prevalence of hepatitis markers in an urban university population in order to support the development of a comprehensive program for HBV immunization and HBV/HCV diagnosis. Students, employees, and visitors (n = 2,936, 31 years IQR 24.5-50, female = 69.0% and 81.1% with at least 12 years of education) were enrolled from May to November 2013. Antibodies against hepatitis B surface antigen (anti-HBs), against hepatitis B core antigen (anti-HBc), and hepatitis B surface antigen (HBsAg) were detected with enzyme immunoassays and anti-hepatitis C virus (anti-HCV) antibodies with a chemiluminescence immunoassay. The results were confirmed with polymerase chain reaction for HCV and nucleic acid amplification test for hepatitis B virus (HBV). Results. The overall prevalence of markers among the participants was 0.136% (95% confidence interval [CI]: 0.003-0.270) for HBsAg, 6.44% (95% CI: 5.55-7.33%) for anti-HBc, 50.8% (95% CI: 48.9-52.7%) for anti-HBs > 10 mIU/mL, and 0.44% (95% CI: 0.20-0.68) for anti-HCV. Almost 30.4% had anti-HBs titers > 100 mIU/mL. Participants with a detectable HCV viral load (n = 9) were infected with genotype 1a. Conclusions. In an urban university population, in which 80% of participants had > 11 years of education, prevalence increased with age, and self-declared ethnicity for anti-HBc and with age, marital status and professional activity for anti-HCV antibodies. A periodical offer of HCV rapid testing should be implemented, and HBsAg rapid testing should be offered to individuals above 20 years of age |
| Disciplinas: | Medicina |
| Palabras clave: | Diagnóstico, Gastroenterología, Hepatitis B, Hepatitis C, Biomarcadores, Anticuerpos, Epidemiología, Factores de riesgo |
| Keyword: | Medicine, Diagnosis, Gastroenterology, Hepatitis B, Hepatitis C, Biomarkers, Antibodies, Epidemiology, Risk factors |
| Texte intégral: | Texto completo (Ver PDF) |
