| Revue: | Annals of hepatology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000416518 |
| ISSN: | 1665-2681 |
| Autores: | Escobedo Meléndez, Griselda1 Fierro, Nora A1 Roman, Sonia1 Maldonado González, Monserrat1 Zepeda Carrillo, Eloy1 Panduro, Arturo1 |
| Instituciones: | 1Hospital Civil de Guadalajara Fray Antonio Alcalde, Departamento de Biología Molecular en Medicina, Guadalajara, Jalisco. México |
| Año: | 2012 |
| Periodo: | Mar-Abr |
| Volumen: | 11 |
| Número: | 2 |
| Paginación: | 194-201 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Viral hepatitis in children is a major public health problem worldwide. Aim. To evaluate the prevalence of serological markers for hepatitis A, B and C infections in Mexican children diagnosed with hepatitis during a five-year period. Material and methods. A total of 31,818 children admitted to a tertiary level hospital in Mexico from 2005 to 2009 were evaluated for hepatitis. Results. Hepatitis was found in 215 (0.7%) of the children. Serum samples from hepatitis-positive children were screened for anti-HAV IgM, HBsAg, total anti-HBc and anti-HCV. HAV was the leading cause of viral hepatitis (81%), followed by HBV and HCV (3.1 and 2%, respectively), whereas no serological marker was observed in 13.9% of the analyzed samples. Furthermore, when children were categorized by age, a significant increase in anti-HAV detection was observed in school-aged children (7-11 years old) (p < 0.001) and a reduction in adolescents (12-15 years old). Conclusion. In conclusion, hepatitis A is the most prevalent viral hepatitis infection detected in children, followed by HBV and HCV. In addition, the high percentage of hepatitis infections without a known etiological agent and the serological test limitations require the detection of occult HBV, HCV and hepatitis E infections. The age-dependent vulnerability of groups with HAV infections emphasizes the importance of HAV vaccination in young children in Mexico |
| Disciplinas: | Medicina |
| Palabras clave: | Gastroenterología, Salud pública, Pediatría, Marcadores serológicos, Seroprevalencia, Virus de la hepatitis A, Virus de la hepatitis B, Virus de la hepatitis C, Niños, México |
| Keyword: | Gastroenterology, Public health, Pediatrics, Serological markers, Seroprevalence, Hepatitis virus A, Hepatitis virus B, Hepatitis virus C, Children, Mexico |
| Texte intégral: | Texto completo (Ver PDF) |
