Cholestatic hepatitis C after chemotherapy containing rituximab in diffuse large B cell lymphoma



Título del documento: Cholestatic hepatitis C after chemotherapy containing rituximab in diffuse large B cell lymphoma
Revue: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000391058
ISSN: 1665-2681
Autores: 1
1
2
1
1
1
1
1
Instituciones: 1Azienda Ospedaliera San Camillo Forlanini, Roma, Lazio. Italia
2Istituti Fisoterapici Ospedalieri, Dipartimento di Hematologia, Roma, Lazio. Italia
Año:
Periodo: Sep-Oct
Volumen: 14
Número: 5
Paginación: 756-761
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Rituximab is a chimeric anti-CD20 monoclonal antibody that is a widely used for the treatment of B cells non-Hodgkin lymphoma. The use of chemotherapy regimens containing rituximab in HCV-positive patients with non-Hodgkin lymphoma has been associated with liver dysfunction, but no cases of cholestatic hepatitis C were described. To our knowledge, this is the first case of cholestatic hepatitis C in an HCV-positive patient with diffuse large B-cell lymphoma describes in the literature. We discuss the pathogenetic mechanisms underlying this severe form of hepatitis and describe its evolution after antiviral treatment
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Oncología,
Inmunología,
Daño hepático,
Inmunosupresión,
Rituximab,
Hepatitis C
Keyword: Medicine,
Gastroenterology,
Oncology,
Immunology,
Liver damage,
Immunosuppression,
Rituximab,
Hepatitis C
Texte intégral: Texto completo (Ver PDF)