An autoimmune polyglandular syndrome complicated with celiac disease and autoimmune hepatitis



Título del documento: An autoimmune polyglandular syndrome complicated with celiac disease and autoimmune hepatitis
Revue: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000407487
ISSN: 1665-2681
Autores: 1
1
1
1
Instituciones: 1Hospital Clínico San Carlos, Instituto de Investigación Sanitaria, Madrid. España
Año:
Periodo: Jul-Ago
Volumen: 15
Número: 4
Paginación: 588-591
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Autoimmune polyglandular syndrome (APS) is a combination of different autoimmune diseases. The close relationship between immune-mediated disorders makes it mandatory to perform serological screening periodically in order to avoid delayed diagnosis of additional autoimmune diseases. We studied a patient with type 1 diabetes (T1D) who later developed an autoimmune thyroid disease (ATD) and was referred to our hospital with a serious condition of his clinical status. The patient was suffering from an advance stage of celiac disease (CD), the delay in its diagnosis and in the establishment of a gluten-free dietled the patient to a severe proteincalorie malnutrition. Later, the patient developed an autoimmune hepatitis (AIH). We consider that clinical deterioration in patients with APS should alert physicians about the possible presence of other immune-mediated diseases. Periodic screening for autoantibodies would help to prevent delayed diagnosis and would improve patient’s quality of life
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Metabolismo y nutrición,
Inmunología,
Enfermedades autoinmunes,
Enfermedad celíaca,
Síndrome poliglandular autoinmune,
Hepatitis autoinmune,
Autoanticuerpos
Keyword: Medicine,
Gastroenterology,
Metabolism and nutrition,
Immunology,
Autoimmune diseases,
Celiac disease,
Autoimmune polyglandular syndrome,
Autoimmune hepatitis,
Autoantibodies
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