Acute hepatitis E mimicking a flare of disease in a patient with chronic autoimmune hepatitis

Título del documento: Acute hepatitis E mimicking a flare of disease in a patient with chronic autoimmune hepatitis
Revue: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000406069
ISSN: 1665-2681
Autores: 1

Instituciones: 1Royal Free London NHS Foundation Trust, Department of Virology, Londres. Reino Unido
2University College London, Royal Free and University College Medical School, Londres. Reino Unido
Periodo: Ene-Feb
Volumen: 16
Número: 1
Paginación: 160-163
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico
Resumen en inglés Acute hepatitis E is becoming increasingly recognised in Europe with up to 40% of the population in Southern France being exposed to the virus, which is harboured in pigs. Patients with known liver disease may present with acute hepatitis E and present a diagnostic challenge. For example patients with autoimmune hepatitis (AIH) who are immunosuppressed and contract hepatitis E may be at increased risk of developing chronicity due to concurrent immunosuppression. Importantly, the diagnosis may be missed with the infection misdiagnosed as an autoimmune flare, and immunosuppression increased by the attending physician, thus enhancing the risk of chronicity of infection leading to progressive liver injury in immunocompromised patients. We report a case of acute hepatitis E in a patient with AIH and discuss the features that helped us differentiating it from an autoimmune flare
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Hepatitis E,
Hepatitis autoinmune,
Keyword: Medicine,
Hepatitis E,
Autoimmune hepatitis,
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