Revue: | Anais da Academia Brasileira de Ciencias |
Base de datos: | PERIÓDICA |
Número de sistema: | 000436285 |
ISSN: | 0001-3765 |
Autores: | Celik, Hakim1 Kilic, Tugba2 Kaplan, Davut S2 Eren, Mehmet A1 Erel, Ozcan3 Karakilcik, Ali Z1 Bagci, Cahit4 |
Instituciones: | 1Harran University, Medical Faculty, Sanliurfa, Harran. Turquía 2Gaziantep University, Medical Faculty, Gaziantep. Turquía 3Yildirim Beyazit University, Medical Faculty, Ankara. Turquía 4Sakarya University, Medical Faculty, Sakarya. Turquía |
Año: | 2019 |
Volumen: | 91 |
Número: | 4 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Analítico, descriptivo |
Resumen en inglés | We studied dynamic thiol/disulphide homeostasis, an indicator of oxidative stress, to investigate the effects of newly initiated exercise training on sedentary obese adults. Seventeen sedentary obese adults and 15 normal-weight controls were included in the sample for this study. The obese adults were given a physical exercise training program that lasted twelve weeks. Before and after the exercise training program, blood samples were collected, and serum thiol/disulphide parameters were measured by using a novel technique. Before the start of the exercise training, it was observed that thiol/disulphide homeostasis was impaired, and this impairment was positively correlated with body mass index in sedentary obese adults because of the higher reactive oxygen species production in adipose tissue. However, while the obese participants’ body mass index significantly decreased, the thiol/disulphide homeostasis parameters in the obese adults did not change over time as calculated at the baseline and compared to the calculation after the twelve weeks of exercise training. Despite a decrease in body mass index that occurred after the twelve weeks of exercise training, there was a lack of improvement in the obesity-induced impairment of thiol/disulphide homeostasis, which suggests that a newly initiated exercise training program may lead to oxidative stress |
Disciplinas: | Medicina |
Palabras clave: | Metabolismo y nutrición, Terapéutica y rehabilitación, Obesidad, Estrés oxidativo, Ejercicio físico, Homeostasis, Tiol-disulfuro |
Keyword: | Metabolism and nutrition, Therapeutics and rehabilitation, Homeostasis, Physical exercise, Obesity, Oxidative stress, Thiol-disulphide |
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