| Revue: | Anais da Academia Brasileira de Ciencias |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000408939 |
| ISSN: | 0001-3765 |
| Autores: | Lourith, Nattaya1 Kanlayavattanakul, Mayuree2 Chaikul, Puxvadee2 Chansriniyom, Chaisak3 Bunwatcharaphansakun, Pichaporn4 |
| Instituciones: | 1Mae Fah Luang University, School of Cosmetic Science, Chiang Rai. Tailandia 2Mae Fah Luang University, Phytocosmetics and Cosmeceuticals Research Group, Chiang Rai. Tailandia 3Chulalongkorn University, Bangkok, Phra Nakhon. Tailandia 4National Science and Technology Development Agency, National Nanotechnology Center, Pathum Thani. Tailandia |
| Año: | 2017 |
| Periodo: | May |
| Volumen: | 89 |
| Paginación: | 577-589 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Peel extracts of litchi and rambutan, and that of tamarind seed coat were investigated in relation to their utility in skin-aging treatments. Standardized extracts of tamarind were significantly ( p < 0.05) more efficient at O 2 •- scavenging (IC 50 = 27.44 ± 0.09) than those of litchi and rambutan (IC 50 = 29.57 ± 0.30 and 39.49 ± 0.52 μg/ml, respectively) and the quercetin standard (IC 50 = 31.88 ± 0.15 μg/ml). Litchi extract proved significantly ( p < 0.05) more effective for elastase and collagenase inhibition (88.29 ± 0.25% and 79.46 ± 0.92%, respectively) than tamarind (35.43 ± 0.68% and 57.69 ± 5.97%) or rambutan (31.08 ± 0.38% and 53.99 ± 6.18%). All extracts were safe to human skin fibroblasts and inhibit MMP-2, with litchi extract showing significantly ( p < 0.01) enhanced inhibition over the standard, vitamin C (23.75 ± 2.74% and 10.42 ± 5.91% at 0.05 mg/ml, respectively). Extracts suppress melanin production in B16F10 melanoma cells through inhibition of tyrosinase and TRP-2, with litchi extract being the most potent, even more so than kojic acid (standard). These results highlight the potential for adding value to agro-industrial waste, as the basis for the sustainable production of innovative, safe, anti-aging cosmetic products |
| Disciplinas: | Química, Agrociencias |
| Palabras clave: | Fitoquímica, Química farmacéutica, Fitotecnia, Frutales, Residuos agroindustriales, Antioxidantes, Actividad celular, Cosméticos, Inhibición enzimática, Cultivos |
| Keyword: | Chemistry, Agricultural sciences, Medicinal chemistry, Phytochemistry, Crop husbandry, Fruit trees, Agroindustrial wastes, Antioxidants, Cellular activity, Cosmetics, Enzyme inhibition, Cultivars |
| Texte intégral: | Texto completo (Ver PDF) |
