Fetal lesions of EHV-1 in equine



Título del documento: Fetal lesions of EHV-1 in equine
Revue: Anais da Academia Brasileira de Ciencias
Base de datos: PERIÓDICA
Número de sistema: 000436037
ISSN: 0001-3765
Autores: 1
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Instituciones: 1Zagazig University, Faculty of Veterinary Medicine, Zagazig, Sharqiya. Egipto
2Thamar University, Faculty of Veterinary Medicine, Dhamar. Yemen
3Djibouti Regional Livestock Quarantine, Damerjog. Yibuti
Año:
Volumen: 92
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Aplicado, descriptivo
Resumen en inglés EHV-1 infection is responsible for huge economic losses in equines due to abortion and neonatal mortality. In this study, we describe 4 cases of abortion and neonatal deaths from pregnant mares and a she-donkey from different localities in Egypt during the period from May 2015 to October 2017. Attempts were made to isolate and identify EHV-1, in addition to compare the different pathological lesions in various tissues of the necropsied cases. EHV-1 was successfully isolated from two aborted fetuses and one dead neonatal foal from mares, beside one aborted fetus from a she-donkey. The positive cases showed cytopathic effect on embryonated chicken eggs scattered on chorioallantoic membrane. Moreover, PCR was applied for the pock lesions and revealed positive results for EHV-1. Interstitial pneumonia, bronchopneumonia and necrosis of hepatic, myocardial, microcotyledonary tissues besides disseminated thrombi were the main encountered lesions. Intranuclear inclusion bodies were demonstrated in brain, liver, placenta and pulmonary tissues. Here, we describe EHV-1 induced brain lesions represented by degenerated neurons, vascular endotheliosis with intranuclear inclusion bodies in the aborted she-donkey fetus. Lesions were more sever in the aborted fetuses from mares than the one from the she-donkey. EHV-1 antigen was detected by immunohistochemistry staining
Disciplinas: Medicina veterinaria y zootecnia
Palabras clave: Equinos,
Reproducción y genética animal,
Yeguas,
Lesión fetal,
Herpesvirus equino,
Aborto
Keyword: Equines,
Animal reproduction and genetics,
Mares,
Abortion,
Equine herpesvirus,
Fetal lesion
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