Assessment of adiposity in psoriatic patients by dual energy X-ray absorptiometry compared to conventional methods



Título del documento: Assessment of adiposity in psoriatic patients by dual energy X-ray absorptiometry compared to conventional methods
Revue: Anais brasileiros de dermatologia
Base de datos: PERIÓDICA
Número de sistema: 000395841
ISSN: 0365-0596
Autores: 1
2
1
1
1
2
Instituciones: 1Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais. Brasil
2Santa Casa de Belo Horizonte, Belo Horizonte, Minas Gerais. Brasil
Año:
Periodo: Mar-Abr
Volumen: 91
Número: 2
Paginación: 150-155
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Obesity is considered a chronic low-grade inflammatory disease that shares mediators of inflammation with psoriasis, such as TNF-α and IL-6. The relationship between these two conditions involves factors such as predisposition and response to therapy, in addition to an association with cardiovascular disease. OBJECTIVES: The aim of the present study was to investigate the prevalence of adiposity as determined by body mass index (BMI), waist circumference (WC), and dual energy X-ray absorptiometry (DXA) evaluation in patients with psoriasis. METHODS: BMI, WC and body composition by DXA were measured in 42 psoriatic patients without joint complaints and in 41 control patients using standard procedures. In the comparison between cases and controls, we used Pearson’s Χ2 test or Fisher’s exact test, and the nonparametric Mann-Whitney test. The difference between the diverse classification methods for obesity was evaluated using McNemar’s test. To test the level of agreement between those variables, we used the weighted kappa coefficient. RESULTS: There was no difference in the prevalence of obesity among cases and controls. Both BMI and WC had low agreement with measures of body fat evaluated by DXA. With the use of DXA scanning, prevalence of overweight and obesity in patients with psoriasis was 83.3%, which constitutes a strong evidence of the need for intervention on this metabolic parameter. CONCLUSION: Dual energy X-ray absorptiometry was more capable of identifying obesity compared with BMI and WC both in psoriatic and control patients
Disciplinas: Medicina
Palabras clave: Dermatología,
Metabolismo y nutrición,
Obesidad,
Inflamación,
Psoriasis,
Indice de masa corporal,
Circunferencia abdominal
Keyword: Medicine,
Dermatology,
Metabolism and nutrition,
Obesity,
Inflammation,
Psoriasis,
Body mass index,
Abdominal circumference
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