Endoscopic ultrasound guided fine-needle aspiration core biopsy: comparison between an automatic biopsy device and two conventional needle systems



Título del documento: Endoscopic ultrasound guided fine-needle aspiration core biopsy: comparison between an automatic biopsy device and two conventional needle systems
Revue: Acta gastroenterológica latinoamericana
Base de datos: PERIÓDICA
Número de sistema: 000315802
ISSN: 0300-9033
Autores: 1




Instituciones: 1Escola Paulista de Medicina, Divisao de Gastroenterologia, Sao Paulo. Brasil
Año:
Periodo: Jun
Volumen: 38
Número: 2
Paginación: 105-115
País: Argentina
Idioma: Español
Tipo de documento: Artículo
Enfoque: Aplicado
Resumen en español NA10J-1, y en 18/19 (94,7%) con Shot-Gun (p = 0,223). En dos casos las biopsias fueron negativos debido a tumores muy duros. Conclusión: la aguja Shot-Gun ha obtenido mejores muestras para diagnóstico histológico que NA10J-1 aguja y GIP
Resumen en inglés Background: endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) allows cytologic and/or histologic diagnosis of lesions within or adjacent to the gastrointestinal tract. However, the amount of tissue obtained with a regular 22 gauge needle is not always satisfactory. With the development of a needle XNA-10J-KB (Shot-Gun®) that resembles the automatic liver biopsy needle, it is expected that significant samples be obtained more frequently (core biopsy), optimizing histological analysis. Objective: to compare samples obtained with EUS-FNA using 3 different needle systems: GIP, NA-10J-1 and Shot-Gun. Methods: 19 patients underwent EUS-FNA for diagnosis (5) or tumor staging (14). Mean age was 58.9 years (range 27-82), being 50% men. All patients were submitted to EUS-FNA with the 3 needle models. The Shot-Gun model was "shot" when its tip was near the target inside the lesion, followed by aspiration. Samples were submitted for cytologic and histologic examination. Results: mean lesion size was 3.0 cm (range 0.8-5.5 cm). Final diagnoses were made after surgery or intra-operative biopsy: 13 pancreatic tumors (12 adenocarcinomas and 1 neuroendocrine tumor), 4 chronic pancreatitis, 1 acute pancreatitis, and 1 cholangiocarcinoma. Specimens adequate for cytologic diagnosis were obtained in 13/19 (68.4%) patients using GIP model, in 14/19 (73.7%) with NA10J-1 model, and in 17/19 (89.5%) with Shot- Gun‚ model (p=0.039). Histologic analysis was possible in 10/19 (52.6%) patients using the GIP model, in 14/19 (73.7%) with NA10J-1, and in 17/19 (89.5%) with Shot-Gun‚ model (p=0.005). Adequate samples for cytologic or histologic assessment in 16/19 (84.2%) patients using the GIP model, in 17/19 (89.5%) with NA10J-1, and in 18/19 (94.7%) with Shot-Gun‚ model (p=0.223). In two cases biopsies were negative due to very hard tumors. Conclusion: the Shot- Gun needle obtained better samples for histological diagnosis than NA10J-1 needle and GIP
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Gastroenterología,
Biopsia,
Aguja fina,
Endoscopia,
Ultrasonido,
Neoplasias,
Páncreas
Keyword: Medicine,
Diagnosis,
Gastroenterology,
Biopsy,
Fine needle,
Endoscopy,
Ultrasound,
Neoplasms,
Pancreas
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