Virulence exaltation of Clostridium perfringens strains from bovines



Document title: Virulence exaltation of Clostridium perfringens strains from bovines
Journal: The journal of venomous animals and toxins including tropical diseases
Database: PERIÓDICA
System number: 000298819
ISSN: 1678-9199
Authors: 1
2
3
4
Institutions: 1Instituto Biologico, Secao de Bacteriologia Geral e Micobacterioses, Sao Paulo. Brasil
2Instituto Adolfo Lutz, Sao Paulo. Brasil
3Universidade Camilo Castelo Branco, Fernandopolis, Sao Paulo. Brasil
4Universidade de Sao Paulo, Instituto de Ciencias Biomedicas, Sao Paulo. Brasil
Year:
Volumen: 10
Number: 3
Pages: 280-292
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental
English abstract Ten out of eighty-nine strains biochemically identified as Clostridium perfringens, isolated from bovine organs, were selected by their different results showed in toxigenicity test on mice. Those and the standard strains, ATCC types A, B, C, and D, had their virulence exalted through serial intramuscular inoculation into guinea pigs. Results showed that, for toxigenic strains (6), one or two passages were enough to cause exaltation, while for the atoxigenic (4), five or six inoculations were needed. Esterase electrophoresis of standard and isolated strains, with and without exaltation, was performed. Electrophoresis analysis permits the following conclusions: strains that do not show any clinical symptoms in mice, when exalted demonstrate decreased esterase activity; on the contrary, it is increased when correlated with animal symptoms
Disciplines: Biología,
Medicina veterinaria y zootecnia
Keyword: Bovinos,
Medicina veterinaria,
Microbiología,
Clostridium perfringens,
Electroforesis,
Virulencia
Keyword: Biology,
Veterinary medicine and animal husbandry,
Bovines,
Veterinary medicine,
Microbiology,
Clostridium perfringens,
Electrophoresis,
Virulence
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