Uncommon vancomycin: induced side effects



Document title: Uncommon vancomycin: induced side effects
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290707
ISSN: 1413-8670
Authors: 1



Institutions: 1Hospital Nossa Senhora das Gracas, Divisao de Doencas Infecciosas, Curitiba, Parana. Brasil
Year:
Season: Ago
Volumen: 6
Number: 4
Pages: 196-200
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Caso clínico, descriptivo
English abstract ABSTRACT Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the "red man syndrome". Other adverse effects include neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia, interstitial nephritis, lacrimation, linear IgA bullous dermatosis, necrotizing cutaneous vasculitis and toxic epidermal necrolysis. Only two cases of vancomycin-induced Stevens-Johnson syndrome and one case of pancytopenia have been reported in the medical literature. The treatment for both situations is based on cessation of the vancomycin therapy; in cases of Stevens-Johnson syndrome, antihistamine and/or steroid agents can be used. This article reports a case of pancytopenia and a case of erythema major associated with neutropenia
Disciplines: Medicina,
Biología
Keyword: Dermatología,
Farmacología,
Anatomía e histología,
Vancomicina,
Síndrome de Stevens-Johnson,
Pancitopenia,
Reacciones,
Trombocitopenia
Keyword: Medicine,
Biology,
Dermatology,
Pharmacology,
Anatomy and histology,
Vancomycin,
Stevens-Johnson syndrome,
Pancytopenia,
Reactions,
Thrombocytopenia
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