Journal: | The brazilian journal of infectious diseases |
Database: | PERIÓDICA |
System number: | 000290707 |
ISSN: | 1413-8670 |
Authors: | Rocha, Jaime Luis Lopes1 Kondo, William Baptista, Maria Inez Domingues Kuchiki Cunha, Clovis Arns da Martins, Luzilma Terezinha Flenik |
Institutions: | 1Hospital Nossa Senhora das Gracas, Divisao de Doencas Infecciosas, Curitiba, Parana. Brasil |
Year: | 2002 |
Season: | Ago |
Volumen: | 6 |
Number: | 4 |
Pages: | 196-200 |
Country: | Brasil |
Language: | Inglés |
Document type: | Artículo |
Approach: | Caso clínico, descriptivo |
English abstract | ABSTRACT Vancomycin has been used with increased frequency during the past 15 years and the most common toxicity with this drug is the "red man syndrome". Other adverse effects include neutropenia, fever, phlebitis, nephrotoxicity, ototoxicity, thrombocytopenia, interstitial nephritis, lacrimation, linear IgA bullous dermatosis, necrotizing cutaneous vasculitis and toxic epidermal necrolysis. Only two cases of vancomycin-induced Stevens-Johnson syndrome and one case of pancytopenia have been reported in the medical literature. The treatment for both situations is based on cessation of the vancomycin therapy; in cases of Stevens-Johnson syndrome, antihistamine and/or steroid agents can be used. This article reports a case of pancytopenia and a case of erythema major associated with neutropenia |
Disciplines: | Medicina, Biología |
Keyword: | Dermatología, Farmacología, Anatomía e histología, Vancomicina, Síndrome de Stevens-Johnson, Pancitopenia, Reacciones, Trombocitopenia |
Keyword: | Medicine, Biology, Dermatology, Pharmacology, Anatomy and histology, Vancomycin, Stevens-Johnson syndrome, Pancytopenia, Reactions, Thrombocytopenia |
Full text: | Texto completo (Ver HTML) |