| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290728 |
| ISSN: | 1413-8670 |
| Authors: | Conterno, Lucieni de Oliveira1 Wey, Sergio Barsanti2 Castelo, Adauto |
| Institutions: | 1Faculdade de Medicina de Marilia, Marilia, Sao Paulo. Brasil 2Universidade Federal de Sao Paulo, Divisao de Doencas Infecciosas, Sao Paulo. Brasil |
| Year: | 2002 |
| Season: | Dic |
| Volumen: | 6 |
| Number: | 6 |
| Pages: | 288-297 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental |
| English abstract | Staphylococcus aureus is an important pathogen causing bacteremia, primarily affecting hospitalized patients. We studied the epidemiology of S. aureus bacteremia, comparing two periods (early and mid 1990s) and developed a predictive model of mortality. A nested case-control was done. All 251 patients over 14 years old with positive blood cultures for S. aureus were selected. MRSA (methicillin resistant S. aureus) was isolated in 63% of the cases. When comparing the two periods MRSA community-acquired bacteremia increased from 4% to 16% (p=0.01). There was no significant difference in the mortality rate between the two periods (39% and 33%, p=0.40). Intravascular catheters provoked 24% of the cases of bacteremia and were associated with the lowest rate of mortality. In a logistic regression analysis, three variables were associated with death: septic shock, source of bacteraemia and resistance to methicillin. The probability of dying among patients with MRSA and those with methicillin sensitive S. aureus bacteraemia ranged from 10% to 90% and from 4% to 76%, respectively, depending on the source of the bacteraemia and the occurrence of septic shock. The MRSA found in Brazil may be a particularly virulent strain |
| Disciplines: | Medicina |
| Keyword: | Hematología, Microbiología, Salud pública, Staphylococcus aureus, Bacteremia, Mortalidad |
| Keyword: | Medicine, Hematology, Microbiology, Public health, Staphylococcus aureus, Bacteremia, Mortality |
| Full text: | Texto completo (Ver HTML) |
