Secretory immunoglobulin A: a protective factor in the genital mucosa



Document title: Secretory immunoglobulin A: a protective factor in the genital mucosa
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290991
ISSN: 1413-8670
Authors: 1
2
3
Institutions: 1Universidade Estadual de Campinas, Campinas, Sao Paulo. Brasil
2Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte. Brasil
3Universidade Federal do Ceara, Fortaleza, Ceara. Brasil
Year:
Season: Ago
Volumen: 10
Number: 4
Pages: 232-234
Country: Brasil
Language: Inglés
Document type: Reporte técnico
Approach: Caso clínico
English abstract The genital mechanisms of defense are not well understood and are therefore ignored during therapy. This fact results in a great number of cases of treatment failure. The mucosa is an important protective factor of the genital female system, through self-defense mechanisms, and secretor antibodies (immunoglobulin A). The lymphoid tissue exerts protective anti-inflammatory activity, besides inhibiting microorganism adherence, neutralizes viruses and toxins and stabilizes the mucosal flora. Although certain microorganisms, such as viruses and fungus, are controlled by cellular immunity, secretory IgA can also exert an important role in the control of these agents
Disciplines: Medicina
Keyword: Ginecología y obstetricia,
Microbiología,
Inmunología,
Vagina,
Infecciones,
Mucosa,
Virus del papiloma humano,
Candida albicans,
Inmunoglobulina A (IgA)
Keyword: Medicine,
Gynecology and obstetrics,
Microbiology,
Vagina,
Infections,
Human papillomavirus,
Candida albicans,
IgA,
Immunology,
Mucosa
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