| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000291041 |
| ISSN: | 1413-8670 |
| Authors: | Silva, Nanci1 Oliveira, Marcio2 Bandeira, Antonio Carlos Brites, Carlos |
| Institutions: | 1Universidade Federal da Bahia, Escola de Medicina e Saude Publica, Salvador, Bahia. Brasil 2Hospital Espanhol, Salvador, Bahia. Brasil |
| Year: | 2006 |
| Season: | Jun |
| Volumen: | 10 |
| Number: | 3 |
| Pages: | 191-193 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental |
| English abstract | Nosocomial infection caused by extended-spectrum beta-lactamase producing Klebsiella pneumoniae (ESBL-Kp) have been frequently reported worldwide. We have no information on such problems in Bahia, Brazil. OBJECTIVES: Evaluate the risk factors for nosocomial infections caused by ESBL-Kp, in a tertiary hospital, in Bahia, Brazil. MATERIAL AND METHODS: We evaluated all reported cases of nosocomial infections caused by ESBL-Kp in a private, tertiary hospital, in Salvador, Brazil, from 2000 through 2004. We compared patients with a diagnosis of ESBL-Kp (cases) and patients infected by non-ESBL producing K. pneumoniae (controls). Mean age, underlying disease, and frequency of invasive procedures were compared between the two groups. History of previous use of antibiotics was also analyzed. RESULTS: Based on multivariate analysis, previous use of antibiotics, diagnosis of malignant diseases, and diabetes mellitus were independent risk factors for acquisition of ESBL-Kp infection. No correlation was found for age, use of corticosteroids, diagnosis of chronic renal failure or AIDS, and infection by ESBL-Kp. CONCLUSION: Our findings suggest that the use of antibiotics or underlying disease that increases the chance of antibiotic are the main risk factors for ESBL-Kp infections. Programs focusing on rational use of antibiotics are mandatory for prevention and control of such infections |
| Disciplines: | Medicina |
| Keyword: | Farmacología, Hospitales, Microbiología, Infección hospitalaria, ESBL, Klebsiella pneumoniae, Resistencia bacteriana |
| Keyword: | Medicine, Hospitals, Microbiology, Pharmacology, Nosocomial infections, ESBL, Klebsiella pneumoniae, Bacterial resistance |
| Full text: | Texto completo (Ver HTML) |
