Prevalence of Mycobacterium avium and Mycobacterium tuberculosis in blood cultures of Brazilian AIDS patients after introduction of highly active retroviral therapy



Document title: Prevalence of Mycobacterium avium and Mycobacterium tuberculosis in blood cultures of Brazilian AIDS patients after introduction of highly active retroviral therapy
Journal: The brazilian journal of infectious diseases
Database: PERIÓDICA
System number: 000290898
ISSN: 1413-8670
Authors: 1
2

3
Institutions: 1Laboratorio Central do Estado do Parana, Curitiba, Parana. Brasil
2Universidade Federal do Parana, Departamento de Patologia Clinica, Curitiba, Parana. Brasil
3Universidade Federal do Parana, Departamento de Infectologia, Curitiba, Parana. Brasil
Year:
Season: Dic
Volumen: 9
Number: 6
Pages: 459-463
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Caso clínico
English abstract The use of highly active antiretroviral therapy (HAART) for the treatment of HIV infection has been associated with a marked reduction in the incidence of most opportunistic infections. From April 2001 to February 2002, 80 blood samples from patients who were suspected to have disseminated mycobacterial infection, presenting fever and (preferably) a CD4 T cell count < 100.0 cell/mL were investigated. Twelve (15%) of the 80 blood cultures were positive for mycobacteria, with Mycobacterium avium being identified in 7 (8.8%) samples and M. tuberculosis in 5 (6.2%). The TCD4+ count at the time of M. avium bacteremia ranged from 7cells/µL (average of 48.5 cell/µL), while in M. tuberculosis bacteremia it ranged from 50.0 cells/µL (average of 80.0 cell/µL). The prevalence of M. avium bacteremia in our study follows the expected decline in opportunistic infections observed after the introduction of HAART; however, mycobacteremia by M. tuberculosis still indicates a high prevalence of tuberculosis infection in AIDS patients
Disciplines: Medicina
Keyword: Microbiología,
Terapéutica y rehabilitación,
Inmunología,
Terapia antirretroviral,
Bacteremia,
Mycobacterium avium,
Mycobacterium tuberculosis,
SIDA
Keyword: Medicine,
Microbiology,
Therapeutics and rehabilitation,
Antiretroviral therapy,
Bacteremia,
Mycobacterium avium,
Mycobacterium tuberculosis,
AIDS,
Immunology
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