| Journal: | The brazilian journal of infectious diseases |
| Database: | PERIÓDICA |
| System number: | 000290672 |
| ISSN: | 1413-8670 |
| Authors: | Carvalho, Cristiana M.C. Nascimento1 Lopes, Antonio A2 Gomes, Maria Daniela B.S Magalhaes, Morgana P Oliveira, Juliana R3 Vilas-Boas, Ana Luisa Ferracuti, Roberta Brandileone, Maria Cristina C4 Guerra, Maria Luiza L.S Alves, Noraney N Athayde, Ledilce A Caldas, Renilza M Barberino, Maria Goreth M.A5 Duarte, Jussara Brandao, Maria Angelica S6 Rocha, Heonir Benguigui, Yehuda7 Fabio, Jose Luis di |
| Institutions: | 1Universidade Federal da Bahia, Departamento de Pediatria, Salvador, Bahia. Brasil 2Universidade Federal da Bahia, Medicina Interna, Salvador, Bahia. Brasil 3Universidade Federal da Bahia, Faculdade de Medicina, Salvador, Bahia. Brasil 4Instituto Adolfo Lutz, Secao de Bacteriologia, Sao Paulo. Brasil 5Hospital Alianca, Salvador, Bahia. Brasil 6Laboratorio Central da Bahia, Salvador, Bahia. Brasil 7Organización Panamericana de la Salud, Washington, Distrito de Columbia. Estados Unidos de América |
| Year: | 2001 |
| Season: | Feb |
| Volumen: | 5 |
| Number: | 1 |
| Pages: | 13-20 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Caso clínico, analítico |
| English abstract | Pneumonia is one of the leading causes of hospitalization and death among children in developing countries, and mortality due to pneumonia has been associated with S. pneumoniae infection. This investigation was designed to describe the antimicrobial susceptibility and serotype patterns of pneumococcal strains recovered from the blood of children with community-acquired pneumonia (CAP) and to assess the clinical findings of pneumococcal bacteremic patients with pneumonia. In a 26 month prospective study, blood cultures were obtained as often as possible from children (<16 years of age) diagnosed with CAP in two emergency rooms. Antimicrobial drug susceptibility tests and serotyping were performed when pneumococcus was identified. We studied 3,431 cases and cultured blood samples from 65.5% of those. Pneumococcus was recovered from 0.8% of the blood samples. The differences in age, somnolence, wheezing and hospitalization among children with and without pneumococcal bacteremia were statistically significant. Pneumococcal bacteremia was age-related (mean 1.63 ± 1.55; median 0.92) and associated with somnolence and hospitalization among children with CAP. One strain was recovered from pleural fluid. Penicillin resistance was detected in 21.0% (4/19) of the strains at an intermediate level, whereas 63.0% of the strains were resistant to trimethoprim-sulfamethoxazole. The most common serotypes were 14 and 6B, and these serotypes included the resistant strains. Eight of our 18 isolates from blood were of types included in the heptavalent conjugate pneumococcal vaccine, recently licensed in the USA |
| Disciplines: | Medicina |
| Keyword: | Diagnóstico, Neumología, Pediatría, Streptococcus pneumoniae, Resistencia antimicrobiana, Serotipos, Hemocultivo, Neumonía, Niños |
| Keyword: | Medicine, Diagnosis, Pediatrics, Pneumology, Streptococcus pneumoniae, Antimicrobial resistance, Serotypes, Blood culture, Pneumonia, Children |
| Full text: | Texto completo (Ver HTML) |
